Zileuton is used to prevent wheezing, shortness of breath, coughing and chest discomfort associated with asthma. It is not indicated to treat asthma attacks already in progress.
What is Zileuton?
Zileuton is an inhibitor of the synthesis of leukotrienes. It works by blocking the synthesis of substances that cause swelling, mucus production and narrowing of the airways.
How should Zileuton be taken?
Zileuton is taken orally in the form of tablets or extended-release tablets (to be swallowed strictly whole).
Side effects associated with Zileuton
Among the possible adverse effects of Zileuton are included:
- Headache
- Heartburn
- Diarrhea
- Muscle aches
- Irritation of the nose and throat
- Pain or congestion in the face
You should immediately contact a doctor if taking Zileuton triggers any of the following symptoms:
- Rash
- Urticaria
- Pain in the upper right of the abdomen
- Nausea
- Vomiting
- Severe tiredness
- Itching
- Jaundice
- Dark urine
- Flu-like symptoms
Contraindications and warnings associated with the use of Zileuton
Zileuton should not be used to treat an acute asthma attack.
Moreover, before you start treatment you should inform your doctor if:
- You have any allergy to the active substance or any other drug
- You are taking other medications, herbal remedies and supplements, citing particularly anticoagulants, antifungals, beta blockers, calcium channel blockers, cisapride, clarithromycin, cyclosporine, HIV medications, nefazodone, telithromycin and theophylline
- You suffer (or have suffered) from liver disease
- You have ever abused alcohol
- You are pregnant or breastfeeding
