Galantamine is an inhibitor of acetylcholinesterase, the enzyme that at the level of synapses – the contact points between neurons that allow the transmission of nerve impulses from one cell to another – is responsible for the degradation of the neurotransmitter acetylcholine. Its pharmacological effect is based on increasing the amount of dopamine, which is reduced in people with Alzheimer's disease.
What is Galantamine?
Galantamine is used to relieve the symptoms of the disease Alzheimer's disease and vascular dementia. In particular, this drug helps slow the progression of the disease, and counteracts memory loss, confusion and behavioral changes associated with Alzheimer's disease. However, galantamine is not a cure for Alzheimer’s or other forms of dementia for which it may be prescribed.
How should Galantamine be taken?
Galantamine can be taken in the form of capsules with modified-release (to swallow whole) or as a solution for oral use (which can be added to any non-alcoholic beverage). The intake should be done on a full stomach (with a snack or after a meal).
For the treatment to be as effective as possible it is important to carefully follow the instructions of the physician; typically, the initial treatment involves the intake of a low dose that is gradually increased in order to avoid unpleasant side effects. During the treatment it is important to drink plenty of water. In case you miss a dose you can take it when you realize, while avoiding taking two doses at the same time or at very close range.
Side effects associated with Galantamine
The possible side effects associated with galantamine may include:
- Feeling sick or tired
- Indigestion
- Stomach ache
- Diarrhea
- Dizziness
- Fainting
- Drowsiness
- Headache
- Tremors
- Changes in blood pressure
- Loss of appetite
- Weight loss
- Increased sweating
- Mood changes
Contraindications and warnings associated with the use of Galantamine
Prior to undergoing treatment with galantamine it is recommended to inform your doctor if you suffer from allergies related to the active substance or to other medications, if you are pregnant or breast-feeding; if you suffer from liver, kidney, cardiac, and respiratory problems, severe constipation, if you have problems with urination, stomach ulcers or have underwent recent surgery on the stomach, intestines or bladder. Moreover, it is also important to inform your doctor of other medications or supplements taken simultaneously.
