Estrone is used to control symptoms associated with menopause and perimenopause.
What is Estrone?
Estrone is a synthetically prepared or naturally occurring steroidal estrogen. It interacts with estrogen receptors and triggers a cascade of cellular reactions that lead to the regulation of specific genes. In this way, it increases the synthesis of other hormones and proteins and stimulates the release of FSH (follicle stimulating hormone) by the pituitary gland.
How should Estrone be taken?
Estrone can be administered orally or intravenously. It has many different forms such as creams, vaginal suppositories or solutions.
Side effects associated with Estrone
Among the possible side effects of estrone include the following:
- Breast sensitivity and enlargement
- Water retention
- Weight gain
- Reduction in milk production
- Loss of appetite
- Painful menstruation
- Irritation and sinus congestion
- Stomach cramps
- Abdominal swelling
- Vaginal mycosis
- Bronchitis
- Gastrointestinal inflammation
- Endometrial hypertrophy
- Sexual problems
- Diarrhea
- Vaginal discharge
- Dizziness
- Headache or migraine
- Mood swings
- Vomiting
- Blood clots in the blood vessels of the eye
- Long or heavy periods
- Skipped periods
- Acute infections of the nose, throat or sinuses
- Back ache
- Bleeding not associated with a menstrual cycle
- Gall bladder obstruction
- Thrombi
- Pulmonary embolism
- Breast cancer
- Uterine cancer
- Ovarian cancer
- Changes in the curvature of the eye
- Chest pain
- Breast and nipple discharge
- Infarct
- Hepatitis
- High blood pressure
- Involuntary muscle movements
- Breast lumps
- Stroke
- Flu-like symptoms
It is important to contact a doctor immediately if you experience:
- Rash
- Urticaria
- Itch
- Difficulty breathing
- Tightness in the chest
- Swelling of the mouth, face, lips, throat or tongue
Contraindications and warnings associated with the use of Estrone
Before starting treatment with estrone, it is important to tell your doctor if:
- You have any allergies to the active substance, its excipients, or to any other drugs, food and various substances
- You are taking any other medications, herbal remedies or supplements
- You are suffering (or have suffered) from asthma, epilepsy, heart problems, liver or kidney problems, headaches, blood clots, cancer (particularly breast cancer), jaundice, diabetes, endometriosis, or uterine fibroids, gallstones, liver hemangioma, high blood pressure, hypercalcemia and hypocalcemia, hypertriglyceridemia, irritation or vaginal infections, Lupus erythematosus, vaginal problems, porphyria, thyroid disorders, vision problems, vaginal bleeding or genitalia abnormalities of unknown cause
- You have recently suffered from a heart attack or stroke
- You are pregnant or breast-feeding
