Enzalutamide is primarily used to treat certain types of metastatic prostate cancer.
What is Enzalutamide?
Enzalutamide is an antiandrogen. It works by blocking the activity of testosterone.
How should Enzalutamide be taken?
Enzalutamide is typically administered orally in the form of capsules.
Side effects associated with Enzalutamide
Among the possible side effects of Enzalutamide include the following:
- Flu-like symptoms
- Diarrhea
- Dizziness
- Headache
- Hot flashes
- Mild pain in the back, bones, joints or muscles
- Fatigue
- Insomnia
- Weakness
It is important to contact a doctor immediately if you experience:
- Rash
- Urticaria
- Itch
- Difficulty breathing
- Tightness in chest
- Swelling of the mouth, face, lips or tongue
- Anxiety
- Numbness and weakness in the legs
- Change in the amount of urine produced
- Confusion
- Sensitivity to touch
- Tingling, burning or numbness of the skin
- Persistent fever, chills or sore throat
- Hallucinations
- Memory problems
- Muscle weakness or pain
- Pink or red urine
- Convulsions
- Severe testicle pain
- Shortness of breath
- Swelling of the hands, arms, legs or feet
Contraindications and warnings associated with the risk of Enzalutamide
Enzalutamide can compromise the ability to drive or operate hazardous machinery. Its effects can be aggravated by alcohol and other drugs. During treatment with Enzalutamide, it is important to always use a condom during sexual intercourse.
Enzalutamide should not be taken in case of treatment with alfentanil, apixaban, artemether-lumefantrine, avanafil, dihydroergotamine, ergotamine, fentanyl, axitinib, bortezomib, bosutinib, cabazitaxel, crizotinib, cyclosporine, dabigartan, ivacaftor, lurasidone, mifepristone, phenytoin, pimozide, protease inhibitors, quinidine, rilpivirine, rivaroxaban roflumilast, sirolimus, tacrolimus, ticagrelor, vandetanib or vincristine
Before starting treatment with Enzalutamide, it is important to tell your doctor if:
- You have any allergies to the active substance, its excipients, or any other drugs or food
- You are taking any other medications, herbal remedies or supplements. Mentioning in particular: gemfibrozil, itraconazole, bosentan, carbamazepine, efavirenz, etravirine, modanafil, nafcillin, phenobarbital, rifamycins, St. John's wort, alfentanil, apixaban, artemether-lumefantrine, avanafil, dihydroergotamine, ergotamine, fentanyl, axitinib, bortezomib, bosutinib, cabazitaxel, crizotinib, cyclosporine, dabigartan, ivacaftor, lurasidone, mifepristone, phenytoin, pimozide, protease inhibitors, quinidine, rilpivirine, rivaroxaban roflumilast, sirolimus, tacrolimus, ticagrelor, vandetanib, vincristine, brentuzimab, elvitegravir, estradiol valerate, omeprazole, and warfarin ulipristal
- You are suffering (or have suffered) from liver or kidney problems, blood vessel disease, seizures, head injury, stroke or transient ischemic attack
- You are pregnant or breast-feeding
