{"id":52061,"date":"2018-06-19T13:38:48","date_gmt":"2018-06-19T13:38:48","guid":{"rendered":"https:\/\/www.humanitas.net\/?post_type=wiki&#038;p=52061"},"modified":"2018-06-19T13:38:48","modified_gmt":"2018-06-19T13:38:48","slug":"bretilijum","status":"publish","type":"wiki","link":"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/bretilijum\/","title":{"rendered":"Bretilijum"},"content":{"rendered":"<p>Bretilijum inhibira osloba]anje norepinefrina. Ta\u010dan mehanizam dejstva jo\u0161 uvek nije definisan ali s esmatra da deluje putem inhibicije kanala koji su prisutni na membrani nervnih \u0107elija kao i aktivnost odre\u0111enih enzima. Ovo rezultuje antiaritmijskim efektom kao i antifibrilatornim efektom na sr\u010dani rad.<\/p>\n<p>&nbsp;<\/p>\n<h2>\u0160ta predstavlja Bretilijum ?<\/h2>\n<p>Bretilijum se primenjuje u hitnim stanjima kod slu\u010dajeva ventrikularne tahikadrije. U slu\u010daju nastanka ventrikularne fibrilacije, primenjuje se u vidu profilakit\u010dkog I terapeutskog le\u010denja.<\/p>\n<p>&nbsp;<\/p>\n<h2>Kako se primenjuje Bretilijum ?<\/h2>\n<p>&nbsp;<\/p>\n<p>Bretilijum se mo\u017ee primenjivati outem injekcije ili intramuskularno. Administriranje ovog leka vr\u0161i medicinsko osoblje\u00a0 u hitnim slu\u010dajevima.<\/p>\n<h2>Ne\u017eeljeni efekti udru\u017eeni sa primenom Bretilijuma<\/h2>\n<p>Vrtoglavica, ose\u0107aj malaksalosti i nespretnost predstavljaju naj\u010de\u0161\u0107e ne\u017eeljene efekte udru\u017eene sa primenom Bretilijuma.<\/p>\n<p>&nbsp;<\/p>\n<h2>Drugi potencijalni ne\u017eeljeni efekti mogu biti:<\/h2>\n<ul>\n<li>Anksioznost<\/li>\n<li>Crvenilo<\/li>\n<li>Pove\u0107ana u\u010destalost prmaturnih ventrikularnih kontrakcja<\/li>\n<li>Bradikardija<\/li>\n<li>Konfuzija<\/li>\n<li>Blagi konjuktivitis<\/li>\n<li>Dijareja<\/li>\n<li>Poreme\u0107aj funkcije bubrega<\/li>\n<li>Abdominalni bolovi<\/li>\n<li>Gubitak daha<\/li>\n<li>Nastnak aritmija<\/li>\n<li>Emocionalna nestabilnost<\/li>\n<li>Prolazna hipertenzja<\/li>\n<li>Hipertermija<\/li>\n<li>Posturalna hipotenzija<\/li>\n<li>ncreased arrhythmias<\/li>\n<li>Letargija<\/li>\n<li>Mu\u010dnian<\/li>\n<li>Paranoja<\/li>\n<li>Osip<\/li>\n<li>Ose\u0107aj pritiska u grudnom ko\u0161u<\/li>\n<li>Osip<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li>Pove\u0107ana hiperesenzitivnost<\/li>\n<li>Sinkopa<\/li>\n<li>Podrigivanje<\/li>\n<li>Znojenje<\/li>\n<li>Vrtoglavica<\/li>\n<li>Povra\u0107anje<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2>Kontraindikacije i mere opreza udru\u017eene sa primenom Bretilijuma<\/h2>\n<p>Pre primene Bretilijuma\u00a0 neophodno je informisati ordiniraju\u0107eg lekara u vezi sa:<\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>U slu\u010daju psotojanja alergija na lekove<\/li>\n<li>U slu\u010daju primene lkova, biljnih preparata il isuplemenata, a anro\u010dito cisaprida, klaritromicina, eritromicina, gatifloksacina, grepafloksacina, levofloksacina, tioridazina, moksifloksacina, ranolazina, telitromicina, tioridazina i glikozida digitalisa.<\/li>\n<li>U slu\u010daju postojanja aortne stenoze, te\u017ee pulmonarne hipertenzije ili drugih kardiovaskualrni poreme\u0107aja<\/li>\n<\/ul>\n","protected":false},"author":11,"featured_media":0,"template":"","wiki-categories":[1795],"wiki-types":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.7.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Bretilijum - Humanitas.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/bretilijum\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Bretilijum - Humanitas.net\" \/>\n<meta property=\"og:description\" content=\"Bretilijum inhibira osloba]anje norepinefrina. 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