{"id":51930,"date":"2018-06-19T08:28:22","date_gmt":"2018-06-19T08:28:22","guid":{"rendered":"https:\/\/www.humanitas.net\/?post_type=wiki&#038;p=51930"},"modified":"2018-06-19T08:29:06","modified_gmt":"2018-06-19T08:29:06","slug":"daunorubicin","status":"publish","type":"wiki","link":"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/daunorubicin\/","title":{"rendered":"Daunorubicin"},"content":{"rendered":"<p>Daunorubicin pripada klasi lekova sa antikanceroznim dejstvom tj. grupi antraciklina.\u00a0 Deluje putem prevencije sinteze DNA i RNA. Daunorubicin usporava ili inhibira prekomerni rast tumorskih \u0107elija.<\/p>\n<p>&nbsp;<\/p>\n<h2>\u0160ta predstavlja Daunorubicin?<\/h2>\n<p>&nbsp;<\/p>\n<p>Daunorubicin se primenjuje u kombinaciji sa drugim anti-kanceroznim lekovima\u00a0 u cilju le\u010denja odre\u0111enih oblika akutne mijeloidne leukemije i akutnelimfocitne leukemije.<\/p>\n<h2>Kako se primenjuje Daunorubicin?<\/h2>\n<p>&nbsp;<\/p>\n<p>Daunorubicin se primenjuje putem injekcije direktno u venski put. U slu\u010daju akutne mijeloidne leukemije, le\u010denje podrazumeva periode dnevne administracije, dok se u slu\u010daju akutne limfocitne leukemije, primena ovog leka vr\u0161i na nedeljnoh bazi.<\/p>\n<p>&nbsp;<\/p>\n<p>Du\u017eina le\u010denja ovim lekom direktno zavisi od vrste primenjenog leka, odgovora na terapiju i vrste karcinoma.<\/p>\n<p>&nbsp;<\/p>\n<h2>Ne\u017eeljeni efekti udru\u017eeni sa primenom daunorubicina<\/h2>\n<p>&nbsp;<\/p>\n<p>Naj\u010de\u0161\u0107i ne\u017eeljeni efekti udru\u017eeni sa priemnom ovog leka mogu biti:<\/p>\n<ul>\n<li>Mu\u010dnina<\/li>\n<li>Povra\u0107anje<\/li>\n<li>Ulkusi usana i \u017edrela<\/li>\n<li>Dijareja<\/li>\n<li>\u017deluda\u010dni bolovi<\/li>\n<li>Gubitak kose<\/li>\n<li>Crvena prebojenost urina<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>U slu\u010daju pojave slede\u0107ih simptoma neophodno je konsultovati ordiniraju\u0107eg lekara:<\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>Crvenilo do pojave bola, otok i ose\u0107aj pe\u010denja na mestu injekcije<\/li>\n<li>Osip<\/li>\n<li>Urtikarija<\/li>\n<li>Svrab<\/li>\n<li>Ote\u017eano disanje ili gutanje<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2>Kontraindikacije i mere opeza udru\u017eene sa primenom Daunorubicina<\/h2>\n<p>&nbsp;<\/p>\n<p>Daunorubicin mo\u017ee pove\u0107ati rizik za nastanal drugih karcinoma i mo\u017ee usloviti pojavu kardiovaskularnih poreme\u0107aja nakon zavr\u0161etka tretmana. Mo\u017ee tako\u0111e redukovati nivo proliferacije \u0107elija ko\u0161tane \u00a0sr\u017ei, te pove\u0107ati rizik za nastanak\u00a0 krvarenja i infekcija.<\/p>\n<p>Prema tome, neophodan je adekvatan monitoring zdravstvenog stanja kao i konsultacija ordiniraju\u0107eg lekara.<\/p>\n<p>&nbsp;<\/p>\n<h2>Pre po\u010detka le\u010denja daunorubicinom, neophodno je informisati ordiniraju\u0107eg lekara u vezi sa:<\/h2>\n<p>&nbsp;<\/p>\n<ul>\n<li>U slu\u010daju alergijske reakcije na aktivnu supstancu, metabolite ili druge lekove<\/li>\n<li>U slu\u010daju primene drugih preparat, biljnih peparat ili suplemenata,a anaro\u010dito azatiopirina, ciklosporina, metrotreksata, takrolimsa i sirolimsa.<\/li>\n<li>U sluaju poreme\u0107aja bubrega ili jetre<\/li>\n<li>U slu\u010daju trudno\u0107e ili dojenja<\/li>\n<li><\/li>\n<\/ul>\n","protected":false},"author":11,"featured_media":0,"template":"","wiki-categories":[1795],"wiki-types":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.7.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Daunorubicin - Humanitas.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/daunorubicin\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Daunorubicin - Humanitas.net\" \/>\n<meta property=\"og:description\" content=\"Daunorubicin pripada klasi lekova sa antikanceroznim dejstvom tj. grupi antraciklina.\u00a0 Deluje putem prevencije sinteze DNA i RNA. Daunorubicin usporava ili inhibira prekomerni rast tumorskih \u0107elija. &nbsp; \u0160ta predstavlja Daunorubicin? &nbsp; Daunorubicin se primenjuje u kombinaciji sa drugim anti-kanceroznim lekovima\u00a0 u cilju le\u010denja odre\u0111enih oblika akutne mijeloidne leukemije i akutnelimfocitne leukemije. 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