{"id":51797,"date":"2018-06-18T11:57:27","date_gmt":"2018-06-18T11:57:27","guid":{"rendered":"https:\/\/www.humanitas.net\/?post_type=wiki&#038;p=51797"},"modified":"2018-06-18T11:58:23","modified_gmt":"2018-06-18T11:58:23","slug":"51797","status":"publish","type":"wiki","link":"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/51797\/","title":{"rendered":"Indinavir"},"content":{"rendered":"<p>Indinavir je inhibitor protease koji redukuje nivoe HIV partikula u cirkualciji ali ne dovodi do izle\u010denja infektivnog procesa.<\/p>\n<h2>\u0160ta je Indinavir?<\/h2>\n<p>Inidnavir se primenjuje u kombinaciji sa drugim lekovima koji redukuju rizik za nastanak HIV infekcije \u0161to podrazumeva ste\u010deni sindrom imunodeficijencije (AIDS). Tako\u0111e se mo\u017ee primenjivati u kombinaciji sa drugim lekovima u cilju redukcije rizika za nastanak infekcije kod osoba eksponiranih virusu.<\/p>\n<h2>Kako se primenjuje Indinavir?<\/h2>\n<p>Indinavir se mo\u017ee primenjivati peroralno u formi kapsula. U principu, savetuje se primena 3 pojedina\u010dne dnevne doze na prazan \u017eeludac (1 sat pre ili 2 sata nakon obroka). Ipak, u slu\u010daju da Indinavir izaziva poreme\u0107aje \u017eeluca, neophodno je da se uzima zajedno sa obrokom (npr. obrano mleko).<\/p>\n<p>&nbsp;<\/p>\n<h2>Ne\u017eeljeni efekti udru\u017eeni sa primenom Indinavira<\/h2>\n<p>&nbsp;<\/p>\n<p>Naj\u010de\u0161\u0107i ne\u017eeljeni efekti udru\u017eeni sa primenom Indinavira mogu biti:<\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>Pove\u0107anje koncentracije glukoze u krvi<\/li>\n<li>Ubrzan sr\u010dani rad<\/li>\n<li>Vrtoglavica<\/li>\n<li>Konfuzija<\/li>\n<li>Unilateralan bol tela<\/li>\n<li>Bol u gornjim partijama abdomena<\/li>\n<li>Mi\u0161i\u0107ni bol ili slabost<\/li>\n<li>\u017dutica<\/li>\n<li>Pojava hematoma ili krvarenja<\/li>\n<li>Bol u le\u0111ima<\/li>\n<li>Glavobolja<\/li>\n<li>Mu\u010dnina<\/li>\n<li>Urtikarija<\/li>\n<li>Bledilo<\/li>\n<li>Gubitak apetita<\/li>\n<li>Svrab<\/li>\n<li>Osip<\/li>\n<li>Pojava krvi u urinu<\/li>\n<li>Simptomi sli\u010dni prehladi<\/li>\n<li>Izra\u017een umor<\/li>\n<li>Tamniji urin<\/li>\n<li>Pojava plikova ili deskvamacije<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2>Kontraindikacije i mere opreza udru\u017eene sa primenom Indinavira:<\/h2>\n<p>&nbsp;<\/p>\n<p>U slu\u010daju le\u010denja Didanozidom, savetuje se primena\u00a0 leka najmanje 1 sat pre ili nakon Indinavira.<\/p>\n<h2>Pre primene Indinavira, neophodno je informisati lekara u slu\u010daju:<\/h2>\n<p>&nbsp;<\/p>\n<ul>\n<li>U slu\u010daju postojanja alergijske reakcije na aktivnu supstancu, metabolite ili druge lekove<\/li>\n<li>U slu\u010daju primene drugih lekova, biljnih preparata ili suplemenata,a naro\u010dito alfuzosina, alprazolama, amjodarona, cisaprida, ergot derivarta, lovastatina i drugih statina, midazolama (peroralno), pimozida, sildenafila i drugih lekova u le\u010denju erektilne disfunkcije, simvastatina, triazolama, bosentana, blokatora kalcijumskih kanala, kolhicina, deksametazona, flutikazona, itrakonazola, ketokonazola, HIV lekova, antiaritmika, imunosupresiva, midazolama (injekcija) fosfodiesteraznih inhibitora, fenobarbitala, fenitoina, rifabutina, rifampicina, salmeterola, tadalafila, trazodona, kao i oralnih suplemenata kao \u0161to su venlafaksin i kantarion.<\/li>\n<li>U slu\u010daju hemofilije, dijabetesa, poreme\u0107aja bubrega ili jetre<\/li>\n<li>U slu\u010daju trudno\u0107e ili dojenja<\/li>\n<\/ul>\n","protected":false},"author":11,"featured_media":0,"template":"","wiki-categories":[1795],"wiki-types":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.7.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Indinavir - Humanitas.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/51797\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Indinavir - Humanitas.net\" \/>\n<meta property=\"og:description\" content=\"Indinavir je inhibitor protease koji redukuje nivoe HIV partikula u cirkualciji ali ne dovodi do izle\u010denja infektivnog procesa. \u0160ta je Indinavir? 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