{"id":51755,"date":"2018-06-18T11:07:52","date_gmt":"2018-06-18T11:07:52","guid":{"rendered":"https:\/\/www.humanitas.net\/?post_type=wiki&p=51755"},"modified":"2018-06-18T11:18:46","modified_gmt":"2018-06-18T11:18:46","slug":"mivakurijum","status":"publish","type":"wiki","link":"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/mivakurijum\/","title":{"rendered":"Mivakurijum"},"content":{"rendered":"

Mivakurijum je visoko selektivni neuromuskularni blokator sa kratkim mehaniymom dejstva i brzom obnovom.\u00a0 Indikovan je u op\u0161toj anesteziji u cilju omogu\u0107avanja intubacije, relaksacije glatke muskulature i olak\u0161ane asistirane respiracije toko operativnih zahvata.<\/p>\n

\u0160ta je Muvakurijum ?<\/h2>\n

Mivakurijum je lek koji pripada grupi lekova koji se zovu mi\u0161i\u0107ni relaksansi. Preciznije, nazivaju se antiholinergici, benzil izohinoloni sa neuromuskularnom blokiraju\u0107om aktivno\u0161\u0107u.<\/p>\n

Mivakurijum predstavlja deo kompetitivnih nedepolarizuju\u0107ih neuromuskularnih blokatora. Ovi lekovi deluju na centralni periferni nervni sistem, prekidaju\u0107i neuromuskularnu transmisiju putem kompeticije sa aktivno\u0161\u0107u neurotransmitera acetilholina kao i redukcije odgovora acetilholinskih receptora oslobo\u0111enih nakon nervnog impulsa.<\/p>\n

Nadalje, Mivakurijum je tako\u0111e deo tubokurarina (grupe\u00a0 <\/span>nedepolarizuu\u0107ih mi\u0161i\u0107nih relaksanata), alkuronijuma, galamin trietiodid, metokurin, pankuronijum, atrakurirum, cisatrakuijum i vekuronijum.<\/p>\n

Kako se primenjuje Mivakurijum ?<\/h2>\n

Mivakurijum je komercijalno dostupan u formi rastvora za injekciju, dizajniranoj za intravensku upotrebu (u vidu bolusa ili kontinuirane infuzije).<\/p>\n

Ne\u017eeljeni efekti udru\u017eeni sa Mivakurijumom<\/h2>\n

Postoji nekoliko ne\u017eeljenih efekata koji mogu nastati usled upotrebe Mivakurijuma:<\/p>\n

\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/span>Op\u0161ti poreme\u0107aji: alegrgijske reakcije<\/p>\n

\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/span>Kardiovaskularni poreme\u0107aji: hipotenzija,hipertenzija, vazodilatacija, tahikardija, bradikardija, hipoksemija<\/p>\n

\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/span>Respiratorni sistem: dispnea, bronhospazam, laringospazam, astma<\/p>\n

\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/span>Mi\u0161i\u0107noskeletni poreme\u0107aji: mi\u0161i\u0107na slabost,<\/p>\n

\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/span>Dermatolo\u0161ki poreme\u0107aji: osip, urtikarija, reakcija na mestu injekcije<\/p>\n

\u00b7\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 <\/span><\/span><\/span><\/p>\n

Kontaindikaicje i mere opreza udru\u017eene sa primenom Mivakurijuma<\/h2>\n

Posebna pa\u017enja se posve\u0107uje administraciji lekova kod pacijenata sa dijagnostikovanom ili susspektnom hipersenzitivno\u0161\u0107u na ovaj produkt. Ovaj lek se primenjuje\u00a0 <\/span>isklju\u010divo u bolnicama ili sli\u010dnim ustanovama, te je zabranjen u komercijalnoj prodaji op\u0161toj populaciji.<\/p>\n

Kao i kod ostalih neuromi\u0161i\u0107nih blokiraju\u0107ih agenasa, doziranje Mivakurijuma bi trebalo biti individualizovano kod svakog pacijenta.<\/p>\n

Preporu\u010duje se oprezan nastavak terapije\u00a0 <\/span>u slu\u010dajevima trudno\u0107e ili dojenja. Njegova primena vr\u0161i se isklju\u010divo pod nadzorom ordiniraju\u0107eg lekara.<\/p>\n","protected":false},"author":11,"featured_media":0,"template":"","wiki-categories":[1795],"wiki-types":[],"yoast_head":"\nMivakurijum - Humanitas.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/mivakurijum\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Mivakurijum - Humanitas.net\" \/>\n<meta property=\"og:description\" content=\"Mivakurijum je visoko selektivni neuromuskularni blokator sa kratkim mehaniymom dejstva i brzom obnovom.\u00a0 Indikovan je u op\u0161toj anesteziji u cilju omogu\u0107avanja intubacije, relaksacije glatke muskulature i olak\u0161ane asistirane respiracije toko operativnih zahvata. \u0160ta je Muvakurijum ? Mivakurijum je lek koji pripada grupi lekova koji se zovu mi\u0161i\u0107ni relaksansi. Preciznije, nazivaju se antiholinergici, benzil izohinoloni sa […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/mivakurijum\/\" \/>\n<meta property=\"og:site_name\" content=\"Humanitas.net\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/HumanitasInternational\/\" \/>\n<meta property=\"article:modified_time\" content=\"2018-06-18T11:18:46+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary\" \/>\n<meta name=\"twitter:site\" content=\"@humanitasmilano\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/mivakurijum\/\",\"url\":\"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/mivakurijum\/\",\"name\":\"Mivakurijum - Humanitas.net\",\"isPartOf\":{\"@id\":\"https:\/\/www.humanitas.net\/sr\/#website\"},\"datePublished\":\"2018-06-18T11:07:52+00:00\",\"dateModified\":\"2018-06-18T11:18:46+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/mivakurijum\/#breadcrumb\"},\"inLanguage\":\"sr\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/mivakurijum\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/mivakurijum\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.humanitas.net\/sr\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Wikis\",\"item\":\"https:\/\/www.humanitas.net\/sr\/wiki\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Mivakurijum\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.humanitas.net\/sr\/#website\",\"url\":\"https:\/\/www.humanitas.net\/sr\/\",\"name\":\"Humanitas.net\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/www.humanitas.net\/sr\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.humanitas.net\/sr\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"sr\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.humanitas.net\/sr\/#organization\",\"name\":\"Humanitas\",\"url\":\"https:\/\/www.humanitas.net\/sr\/\",\"sameAs\":[\"https:\/\/www.facebook.com\/HumanitasInternational\/\",\"https:\/\/twitter.com\/humanitasmilano\"],\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"sr\",\"@id\":\"https:\/\/www.humanitas.net\/sr\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.humanitas.net\/content\/uploads\/2017\/05\/logo-news-.png\",\"contentUrl\":\"https:\/\/www.humanitas.net\/content\/uploads\/2017\/05\/logo-news-.png\",\"width\":314,\"height\":61,\"caption\":\"Humanitas\"},\"image\":{\"@id\":\"https:\/\/www.humanitas.net\/sr\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Mivakurijum - Humanitas.net","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/mivakurijum\/","og_locale":"en_US","og_type":"article","og_title":"Mivakurijum - Humanitas.net","og_description":"Mivakurijum je visoko selektivni neuromuskularni blokator sa kratkim mehaniymom dejstva i brzom obnovom.\u00a0 Indikovan je u op\u0161toj anesteziji u cilju omogu\u0107avanja intubacije, relaksacije glatke muskulature i olak\u0161ane asistirane respiracije toko operativnih zahvata. \u0160ta je Muvakurijum ? Mivakurijum je lek koji pripada grupi lekova koji se zovu mi\u0161i\u0107ni relaksansi. Preciznije, nazivaju se antiholinergici, benzil izohinoloni sa […]","og_url":"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/mivakurijum\/","og_site_name":"Humanitas.net","article_publisher":"https:\/\/www.facebook.com\/HumanitasInternational\/","article_modified_time":"2018-06-18T11:18:46+00:00","twitter_card":"summary","twitter_site":"@humanitasmilano","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/mivakurijum\/","url":"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/mivakurijum\/","name":"Mivakurijum - Humanitas.net","isPartOf":{"@id":"https:\/\/www.humanitas.net\/sr\/#website"},"datePublished":"2018-06-18T11:07:52+00:00","dateModified":"2018-06-18T11:18:46+00:00","breadcrumb":{"@id":"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/mivakurijum\/#breadcrumb"},"inLanguage":"sr","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/mivakurijum\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.humanitas.net\/sr\/wiki\/aktivni-sastojci\/mivakurijum\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.humanitas.net\/sr\/"},{"@type":"ListItem","position":2,"name":"Wikis","item":"https:\/\/www.humanitas.net\/sr\/wiki\/"},{"@type":"ListItem","position":3,"name":"Mivakurijum"}]},{"@type":"WebSite","@id":"https:\/\/www.humanitas.net\/sr\/#website","url":"https:\/\/www.humanitas.net\/sr\/","name":"Humanitas.net","description":"","publisher":{"@id":"https:\/\/www.humanitas.net\/sr\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.humanitas.net\/sr\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"sr"},{"@type":"Organization","@id":"https:\/\/www.humanitas.net\/sr\/#organization","name":"Humanitas","url":"https:\/\/www.humanitas.net\/sr\/","sameAs":["https:\/\/www.facebook.com\/HumanitasInternational\/","https:\/\/twitter.com\/humanitasmilano"],"logo":{"@type":"ImageObject","inLanguage":"sr","@id":"https:\/\/www.humanitas.net\/sr\/#\/schema\/logo\/image\/","url":"https:\/\/www.humanitas.net\/content\/uploads\/2017\/05\/logo-news-.png","contentUrl":"https:\/\/www.humanitas.net\/content\/uploads\/2017\/05\/logo-news-.png","width":314,"height":61,"caption":"Humanitas"},"image":{"@id":"https:\/\/www.humanitas.net\/sr\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/www.humanitas.net\/sr\/wp-json\/wp\/v2\/wiki\/51755"}],"collection":[{"href":"https:\/\/www.humanitas.net\/sr\/wp-json\/wp\/v2\/wiki"}],"about":[{"href":"https:\/\/www.humanitas.net\/sr\/wp-json\/wp\/v2\/types\/wiki"}],"author":[{"embeddable":true,"href":"https:\/\/www.humanitas.net\/sr\/wp-json\/wp\/v2\/users\/11"}],"version-history":[{"count":0,"href":"https:\/\/www.humanitas.net\/sr\/wp-json\/wp\/v2\/wiki\/51755\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.humanitas.net\/sr\/wp-json\/wp\/v2\/media?parent=51755"}],"wp:term":[{"taxonomy":"wiki-categories","embeddable":true,"href":"https:\/\/www.humanitas.net\/sr\/wp-json\/wp\/v2\/wiki-categories?post=51755"},{"taxonomy":"wiki-types","embeddable":true,"href":"https:\/\/www.humanitas.net\/sr\/wp-json\/wp\/v2\/wiki-types?post=51755"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}