{"id":36749,"date":"2017-02-14T12:32:08","date_gmt":"2017-02-14T12:32:08","guid":{"rendered":"http:\/\/humanitas.local\/diseases\/charg-shtrausov-sindrom\/"},"modified":"2017-11-06T13:19:19","modified_gmt":"2017-11-06T13:19:19","slug":"charg-shtrausov-sindrom","status":"publish","type":"disease","link":"https:\/\/www.humanitas.net\/sr\/diseases\/charg-shtrausov-sindrom\/","title":{"rendered":"\u010carg-\u0160trausov sindrom"},"content":{"rendered":"

\u010carg-\u0160trausov sindrom (\u010c\u0160S), tako\u0111e poznat i kao Eozinofilna granulomatoza, jedan je od mnogih oblika vaskulitisa, kojeg odlikuje zapaljenje krvnih sudova. Ovo zapaljenje mo\u017ee da ograni\u010di protok krvi do vitalnih organa i tkiva, \u010dime mo\u017ee da uzrokuje njihovo trajno o\u0161te\u0107enje. \u010c\u0160S se javlja kod pacijenata koji imaju astmu ili su imali alergiju, i odlikuje se zapaljenjem krvnih sudova plu\u0107a, ko\u017ee, nerava i abdomena.<\/p>\n

 <\/p>\n

Simptomi<\/h2>\n

\u010c\u0160S je bolest \u010diji simptomi dosta variraju i kod nekih osoba oni mogu biti blagi, dok kod drugih ti simptomi mogu biti izuzetno te\u0161ki i mogu \u010dak ugroziti \u017eivot pacijenta. \u010c\u0160S dovodi do groznice, umora, gubitka te\u017eine, upale sinusa i nosnih \u0161upljina kod osoba koje imaju astmu. Ponekad mo\u017ee do\u0107i do pobolj\u0161anja same astme, dok se ovaj sindrom sa druge strane pogor\u0161ava. Ka\u0161alj, kratak dah, bolovi u grudima mogu da se jave kada su plu\u0107a pogo\u0111ena oboljenjem, dok se na ekstremitetima mogu javiti izrasline. Dijareja i bol u stomaku mogu se javiti zbog upale krvnih sudova u abdomen. Tako\u0111e mo\u017ee do\u0107i do zapaljenja be\u0161ike i prostate.<\/p>\n

Postoje tri stadijuma \u010c\u0160S, svaki od njih ima svoje znake i simptome, ali se ne razvijaju sve tri faze kod svake osobe, niti se ispoljavaju istim redosledom. Ovi stadijumi su:<\/p>\n

Alergi\u010dni stadijum, koji mo\u017ee dovesti do:<\/p>\n

Astme;<\/p>\n

Polenske groznice;<\/p>\n

Bola u sinusima i upali.<\/p>\n

Stadijum hipereozinofilije mo\u017ee da obuhvata:<\/p>\n

Groznicu;<\/p>\n

Gubitak apetita;<\/p>\n

Gubitak te\u017eine;<\/p>\n

Astmu;<\/p>\n

Umor;<\/p>\n

Ka\u0161alj;<\/p>\n

Bol u\u00a0 stomaku;<\/p>\n

Krvarenje u gastrointestinalnom traktu.<\/p>\n

Vaskuliti\u010dni stadijum obuhvata:<\/p>\n

Osip ili rane na ko\u017ei;<\/p>\n

Otok i bol u zglobovima;<\/p>\n

Jaku bol, utrnulost i ose\u0107aj golicanja u rukama i stopalima;<\/p>\n

Jaku bol u stomaku;<\/p>\n

Dijareju, mu\u010dnina i povra\u0107anje;<\/p>\n

Kratak dah zbog astme ili sr\u010dana insuficijencija usled zakr\u010denja krvnih sudova;<\/p>\n

Hemoptiziju (iska\u0161ljavanje krvi);<\/p>\n

Bol u grudima;<\/p>\n

Nepravilni sr\u010dani ritam;<\/p>\n

Hematuriju.<\/p>\n

 <\/p>\n

Uzroci<\/h2>\n

Budu\u0107i da je sam \u010c\u0160S retka bolest, njen uzrok jo\u0161 uvek nije poznat, ali obuhvata abnormalnu preteranu reakciju imunog sistema kod osobe koja ima astmu. U svakom slu\u010daju, da li ona sama dovodi do pojave bolesti, ili pogor\u0161anje, odnosno postojanje te\u0161kog oblika astme dovodi do pove\u0107ane sklonosti ka razvijanju \u010c\u0160S jo\u0161 uvek nije poznato.<\/p>\n

Tako\u0111e je verovatno da je posredi i preterani odgovor, odnosno reakcija imunog sistema izazvana kombinacijom gena i faktora spolja\u0161nje sredine. Umesto da imuni sistem jednostavno \u0161titi organizam od bakterija i virusa, on reaguje preko svake mere i napada sopstvena zdrava tkiva, organe i dovodi do \u0161irenja zapaljenja.<\/p>\n

Kod nekih osoba \u010c\u0160S se javio nakon upotrebe odre\u0111enog leka protiv astme po imenu montelukast, ili nakon prelaska sa oralne upotrebe sistemskih steroida na lekove na bazi steroida koji se uzimaju inhalacijom. Bilo kako bilo, nije dokazana jasna povezanost izme\u0111u \u010c\u0160S i nekog od lekova.<\/p>\n

 <\/p>\n

Komplikacije<\/h2>\n

\u010c\u0160S mo\u017ee da pogodi mnoge organe, uklju\u010duju\u0107i plu\u0107a, ko\u017eu, gastrointestinalni sistem, bubrege, mi\u0161i\u0107e, zglobove i srce. Bez le\u010denja, ova bolest mo\u017ee imati fatalni ishod. Komplikacije zavise od organa koji su zahva\u0107eni bole\u0161\u0107u:<\/p>\n

O\u0161te\u0107enje perifernog nervnog sistema;<\/p>\n

O\u017eiljci na ko\u017ei;<\/p>\n

Bolest srca; ili<\/p>\n

O\u0161te\u0107enje bubrega.<\/p>\n

 <\/p>\n

Faktori rizika<\/h2>\n

Mogu\u0107i faktori rizika za pojavu \u010c\u0160S obuhvataju starosnu dob (ta\u010dnije, vi\u0161e se javlja kod ljudi starijih od 45 godina) kao i kod osoba sa problemima sa astmom i gornjim disajnim putevima.<\/p>\n","protected":false},"author":9,"featured_media":0,"template":"","yoast_head":"\n\u010carg-\u0160trausov sindrom - Humanitas.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.humanitas.net\/sr\/diseases\/charg-shtrausov-sindrom\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u010carg-\u0160trausov sindrom - Humanitas.net\" \/>\n<meta property=\"og:description\" content=\"\u010carg-\u0160trausov sindrom (\u010c\u0160S), tako\u0111e poznat i kao Eozinofilna granulomatoza, jedan je od mnogih oblika vaskulitisa, kojeg odlikuje zapaljenje krvnih sudova. Ovo zapaljenje mo\u017ee da ograni\u010di protok krvi do vitalnih organa i tkiva, \u010dime mo\u017ee da uzrokuje njihovo trajno o\u0161te\u0107enje. \u010c\u0160S se javlja kod pacijenata koji imaju astmu ili su imali alergiju, i odlikuje se zapaljenjem […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.humanitas.net\/sr\/diseases\/charg-shtrausov-sindrom\/\" \/>\n<meta property=\"og:site_name\" content=\"Humanitas.net\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/HumanitasInternational\/\" \/>\n<meta property=\"article:modified_time\" content=\"2017-11-06T13:19:19+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary\" \/>\n<meta name=\"twitter:site\" content=\"@humanitasmilano\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.humanitas.net\/sr\/diseases\/charg-shtrausov-sindrom\/\",\"url\":\"https:\/\/www.humanitas.net\/sr\/diseases\/charg-shtrausov-sindrom\/\",\"name\":\"\u010carg-\u0160trausov sindrom - Humanitas.net\",\"isPartOf\":{\"@id\":\"https:\/\/www.humanitas.net\/sr\/#website\"},\"datePublished\":\"2017-02-14T12:32:08+00:00\",\"dateModified\":\"2017-11-06T13:19:19+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.humanitas.net\/sr\/diseases\/charg-shtrausov-sindrom\/#breadcrumb\"},\"inLanguage\":\"sr\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.humanitas.net\/sr\/diseases\/charg-shtrausov-sindrom\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.humanitas.net\/sr\/diseases\/charg-shtrausov-sindrom\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.humanitas.net\/sr\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Bolesti\",\"item\":\"https:\/\/www.humanitas.net\/sr\/diseases\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"\u010carg-\u0160trausov sindrom\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.humanitas.net\/sr\/#website\",\"url\":\"https:\/\/www.humanitas.net\/sr\/\",\"name\":\"Humanitas.net\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/www.humanitas.net\/sr\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.humanitas.net\/sr\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"sr\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.humanitas.net\/sr\/#organization\",\"name\":\"Humanitas\",\"url\":\"https:\/\/www.humanitas.net\/sr\/\",\"sameAs\":[\"https:\/\/www.facebook.com\/HumanitasInternational\/\",\"https:\/\/twitter.com\/humanitasmilano\"],\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"sr\",\"@id\":\"https:\/\/www.humanitas.net\/sr\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.humanitas.net\/content\/uploads\/2017\/05\/logo-news-.png\",\"contentUrl\":\"https:\/\/www.humanitas.net\/content\/uploads\/2017\/05\/logo-news-.png\",\"width\":314,\"height\":61,\"caption\":\"Humanitas\"},\"image\":{\"@id\":\"https:\/\/www.humanitas.net\/sr\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"\u010carg-\u0160trausov sindrom - Humanitas.net","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.humanitas.net\/sr\/diseases\/charg-shtrausov-sindrom\/","og_locale":"en_US","og_type":"article","og_title":"\u010carg-\u0160trausov sindrom - Humanitas.net","og_description":"\u010carg-\u0160trausov sindrom (\u010c\u0160S), tako\u0111e poznat i kao Eozinofilna granulomatoza, jedan je od mnogih oblika vaskulitisa, kojeg odlikuje zapaljenje krvnih sudova. 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