{"id":63147,"date":"2020-06-22T07:08:44","date_gmt":"2020-06-22T07:08:44","guid":{"rendered":"https:\/\/www.humanitas.net\/?post_type=treatment&p=63147"},"modified":"2020-10-27T11:33:02","modified_gmt":"2020-10-27T11:33:02","slug":"intravitrealno-injiciranje-zdravil-za-bolezni-mreznice","status":"publish","type":"treatment","link":"https:\/\/www.humanitas.net\/sl\/treatments\/intravitrealno-injiciranje-zdravil-za-bolezni-mreznice\/","title":{"rendered":"Intravitrealno injiciranje zdravil za bolezni mre\u017enice"},"content":{"rendered":"

Zdravljenje bolezni mre\u017enice z uporabo intraokularnih injekcij z zdravili<\/h2>\n

\u00a0<\/strong><\/p>\n

V klini\u010dni praksi se \u017ee ve\u010d let uporablja oftalmolo\u0161ka terapija za zdravljenje mre\u017enic z injiciranjem zdravil neposredno v o\u010di. Ta nov terapevtski pristop je izbolj\u0161al prognozo razli\u010dnih bolezni mre\u017enice z zmanj\u0161anjem odstotka poslab\u0161anja vida.<\/p>\n

 <\/p>\n

Kaj je intravitrealno injiciranje zdravil?<\/h2>\n

\u00a0<\/strong><\/p>\n

 <\/p>\n

Zdravila, ki se trenutno uporabljajo in so odobrena za uporabo, so intraokularna zdravila proti VEGF (inhibitorji za tvorbo novih krvnih \u017eil) in kortizon. Prva zdravila (anti VEGF) se uporabljajo pri zdravljenju eksudativne starostne degeneracije makule, diabeti\u010dnega makularnega edema in makularnega edema, ki je posledica tromboze mre\u017enic.<\/p>\n

 <\/p>\n

Druga zdravila (kortizon) so odobrena in se uporabljajo za zdravljenje makularnega edema, ki je povezan s trombozo mre\u017enice in za vnetne o\u010desne bolezni (kot je uveitis).<\/p>\n

Kako deluje intravitrealno injiciranje zdravil?<\/h2>\n

\u00a0<\/strong><\/p>\n

Injekcija se izvaja v nadzorovanem okolju (operacijska dvorana) v sterilnih pogojih in ambulantno. To pomeni, da lahko bolnika po zdravljenju izpustijo iz bolni\u0161nice in zato naj ga spremlja prijatelj ali dru\u017einski \u010dlan. Zdravljenje se izvaja pod lokalno anestezijo ali z vbrizgavanjem anesteti\u010dnih kapljic za oko. Terapija po injiciranju temelji na koloriju. Prvi naknadni pregled opravijo na kliniki naslednji dan. Naslednji pregled bo pribli\u017eno po 2-3 tednih.<\/p>\n

Katere so prednosti in slabosti intravitrealnega injiciranja zdravil?<\/h2>\n

\u00a0<\/strong><\/p>\n

Zdravljenje z intraokularnimi injekcijami je pokazalo dobro u\u010dinkovitost pri zdravljenju razli\u010dnih bolezni mre\u017enice, kot so eksudativna makularna degeneracija, makularni edem, ki je sekundarna diabeti\u010dna retinopatija in venska tromboza. Poro\u010dani ne\u017eeleni u\u010dinki teh zdravljenj so redki, nekateri pa vklju\u010dujejo: povi\u0161an intraokularni tlak, glavobole, vitritis (vnetje o\u010desa), odstranitev stekla, krvavitve mre\u017enice (krvavitve na zadnji strani o\u010desa), motnje vida, bole\u010dine v o\u010deh, stekleni plavalci (pike v vidu), konjunktivalna krvavitev (krvavitev v prednjem delu o\u010desa), dra\u017eenje o\u010di, ob\u010dutek tujega telesa v o\u010desu, pove\u010dano solzenje, blefaritis (vnetje vek), suhe o\u010di, o\u010desna hiperemija (pordelost), pruritus o\u010di, artralgija (bole\u010dine v sklepih) in faringitis nosu (vnetje nosu in \u017erela). V redkih primerih se lahko pojavijo resnej\u0161i zapleti, kot so endoftalmitis (oku\u017eba v o\u010desu), resno vnetje o\u010di, po\u0161kodbe mre\u017enice in katarakte. \u0160e ve\u010d, najresnej\u0161i ali najbolj stra\u0161ljiv sistemski zaplet je tromboembolija.<\/p>\n

 <\/p>\n

Je intravitrealno injiciranje bole\u010de?<\/h2>\n

 <\/p>\n

\u010cas injiciranja je zelo hiter, traja pribli\u017eno 1 minuto, sam ob\u010dutek injiciranja pa pacienta ob\u010duti minimalno.<\/p>\n

 <\/p>\n

Kateri bolniki se lahko zdravijo?<\/h2>\n

 <\/p>\n

Za sistemske bolezni mre\u017enice ni absolutnih kontraindikacij za intravitrealne injekcije. Zlasti pri bolnikih z boleznimi srca in o\u017eilja ali z alergijami na vsebnost zdravil v teh zdravilih obstajajo razli\u010dni dejavniki tveganja.<\/p>\n

 <\/p>\n

Nadaljnje ukrepanje<\/h2>\n

 <\/p>\n

Pregledi, opravljeni po intravitrealnih injekcijah, so prav tako pomembni kot terapija sama. Preglede je treba redno izvajati po navodilih oftalmologa, da se zagotovi ustrezna terapevtska u\u010dinkovitost.<\/p>\n

 <\/p>\n

Standardi priprave<\/h2>\n

 <\/p>\n

Operacija se izvaja v polo\u017eaju na hrbtu, v sterilnem kirur\u0161kem okolju (operacijska dvorana) s pomo\u010djo kirurga, ki operira mikroskop. Operativni poseg je sestavljen iz ve\u010d faz:<\/p>\n

 <\/p>\n

    \n
  • Dezinfekcija ko\u017ee okoli o\u010di in veznice<\/li>\n
  • Intravitrealno injiciranje na 3,5 \/ 4,0 mm od limbusa s transkonjuktivnim pristopom<\/li>\n
  • Intraoperativni nadzor IOP in morebitna paracenteza sprednje komore<\/li>\n<\/ul>\n

     <\/p>\n

    Po posegu bo kirurg dal navodila za pacienta, prilagojena vsakemu posameznemu pacientu.<\/p>\n

     <\/p>\n","protected":false},"author":11,"featured_media":0,"template":"","yoast_head":"\nIntravitrealno injiciranje zdravil za bolezni mre\u017enice - Humanitas.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.humanitas.net\/sl\/treatments\/intravitrealno-injiciranje-zdravil-za-bolezni-mreznice\/\" \/>\n<meta property=\"og:locale\" content=\"sl_SI\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Intravitrealno injiciranje zdravil za bolezni mre\u017enice - Humanitas.net\" \/>\n<meta property=\"og:description\" content=\"Zdravljenje bolezni mre\u017enice z uporabo intraokularnih injekcij z zdravili \u00a0 V klini\u010dni praksi se \u017ee ve\u010d let uporablja oftalmolo\u0161ka terapija za zdravljenje mre\u017enic z injiciranjem zdravil neposredno v o\u010di. Ta nov terapevtski pristop je izbolj\u0161al prognozo razli\u010dnih bolezni mre\u017enice z zmanj\u0161anjem odstotka poslab\u0161anja vida.   Kaj je intravitrealno injiciranje zdravil? \u00a0   Zdravila, ki se […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.humanitas.net\/sl\/treatments\/intravitrealno-injiciranje-zdravil-za-bolezni-mreznice\/\" \/>\n<meta property=\"og:site_name\" content=\"Humanitas.net\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/HumanitasInternational\/\" \/>\n<meta property=\"article:modified_time\" content=\"2020-10-27T11:33:02+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary\" \/>\n<meta name=\"twitter:site\" content=\"@humanitasmilano\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.humanitas.net\/sl\/treatments\/intravitrealno-injiciranje-zdravil-za-bolezni-mreznice\/\",\"url\":\"https:\/\/www.humanitas.net\/sl\/treatments\/intravitrealno-injiciranje-zdravil-za-bolezni-mreznice\/\",\"name\":\"Intravitrealno injiciranje zdravil za bolezni mre\u017enice - Humanitas.net\",\"isPartOf\":{\"@id\":\"https:\/\/www.humanitas.net\/sr\/#website\"},\"datePublished\":\"2020-06-22T07:08:44+00:00\",\"dateModified\":\"2020-10-27T11:33:02+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.humanitas.net\/sl\/treatments\/intravitrealno-injiciranje-zdravil-za-bolezni-mreznice\/#breadcrumb\"},\"inLanguage\":\"sl-SI\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.humanitas.net\/sl\/treatments\/intravitrealno-injiciranje-zdravil-za-bolezni-mreznice\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.humanitas.net\/sl\/treatments\/intravitrealno-injiciranje-zdravil-za-bolezni-mreznice\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.humanitas.net\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Treatments\",\"item\":\"https:\/\/www.humanitas.net\/ro\/treatments\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Intravitrealno injiciranje zdravil za bolezni mre\u017enice\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.humanitas.net\/sr\/#website\",\"url\":\"https:\/\/www.humanitas.net\/sr\/\",\"name\":\"Humanitas.net\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/www.humanitas.net\/sr\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.humanitas.net\/sr\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"sl-SI\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.humanitas.net\/sr\/#organization\",\"name\":\"Humanitas\",\"url\":\"https:\/\/www.humanitas.net\/sr\/\",\"sameAs\":[\"https:\/\/www.facebook.com\/HumanitasInternational\/\",\"https:\/\/twitter.com\/humanitasmilano\"],\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"sl-SI\",\"@id\":\"https:\/\/www.humanitas.net\/sr\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.humanitas.net\/content\/uploads\/2017\/05\/logo-news-.png\",\"contentUrl\":\"https:\/\/www.humanitas.net\/content\/uploads\/2017\/05\/logo-news-.png\",\"width\":314,\"height\":61,\"caption\":\"Humanitas\"},\"image\":{\"@id\":\"https:\/\/www.humanitas.net\/sr\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Intravitrealno injiciranje zdravil za bolezni mre\u017enice - Humanitas.net","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.humanitas.net\/sl\/treatments\/intravitrealno-injiciranje-zdravil-za-bolezni-mreznice\/","og_locale":"sl_SI","og_type":"article","og_title":"Intravitrealno injiciranje zdravil za bolezni mre\u017enice - Humanitas.net","og_description":"Zdravljenje bolezni mre\u017enice z uporabo intraokularnih injekcij z zdravili \u00a0 V klini\u010dni praksi se \u017ee ve\u010d let uporablja oftalmolo\u0161ka terapija za zdravljenje mre\u017enic z injiciranjem zdravil neposredno v o\u010di. Ta nov terapevtski pristop je izbolj\u0161al prognozo razli\u010dnih bolezni mre\u017enice z zmanj\u0161anjem odstotka poslab\u0161anja vida.   Kaj je intravitrealno injiciranje zdravil? \u00a0   Zdravila, ki se […]","og_url":"https:\/\/www.humanitas.net\/sl\/treatments\/intravitrealno-injiciranje-zdravil-za-bolezni-mreznice\/","og_site_name":"Humanitas.net","article_publisher":"https:\/\/www.facebook.com\/HumanitasInternational\/","article_modified_time":"2020-10-27T11:33:02+00:00","twitter_card":"summary","twitter_site":"@humanitasmilano","twitter_misc":{"Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.humanitas.net\/sl\/treatments\/intravitrealno-injiciranje-zdravil-za-bolezni-mreznice\/","url":"https:\/\/www.humanitas.net\/sl\/treatments\/intravitrealno-injiciranje-zdravil-za-bolezni-mreznice\/","name":"Intravitrealno injiciranje zdravil za bolezni mre\u017enice - Humanitas.net","isPartOf":{"@id":"https:\/\/www.humanitas.net\/sr\/#website"},"datePublished":"2020-06-22T07:08:44+00:00","dateModified":"2020-10-27T11:33:02+00:00","breadcrumb":{"@id":"https:\/\/www.humanitas.net\/sl\/treatments\/intravitrealno-injiciranje-zdravil-za-bolezni-mreznice\/#breadcrumb"},"inLanguage":"sl-SI","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.humanitas.net\/sl\/treatments\/intravitrealno-injiciranje-zdravil-za-bolezni-mreznice\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.humanitas.net\/sl\/treatments\/intravitrealno-injiciranje-zdravil-za-bolezni-mreznice\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.humanitas.net\/"},{"@type":"ListItem","position":2,"name":"Treatments","item":"https:\/\/www.humanitas.net\/ro\/treatments\/"},{"@type":"ListItem","position":3,"name":"Intravitrealno injiciranje zdravil za bolezni mre\u017enice"}]},{"@type":"WebSite","@id":"https:\/\/www.humanitas.net\/sr\/#website","url":"https:\/\/www.humanitas.net\/sr\/","name":"Humanitas.net","description":"","publisher":{"@id":"https:\/\/www.humanitas.net\/sr\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.humanitas.net\/sr\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"sl-SI"},{"@type":"Organization","@id":"https:\/\/www.humanitas.net\/sr\/#organization","name":"Humanitas","url":"https:\/\/www.humanitas.net\/sr\/","sameAs":["https:\/\/www.facebook.com\/HumanitasInternational\/","https:\/\/twitter.com\/humanitasmilano"],"logo":{"@type":"ImageObject","inLanguage":"sl-SI","@id":"https:\/\/www.humanitas.net\/sr\/#\/schema\/logo\/image\/","url":"https:\/\/www.humanitas.net\/content\/uploads\/2017\/05\/logo-news-.png","contentUrl":"https:\/\/www.humanitas.net\/content\/uploads\/2017\/05\/logo-news-.png","width":314,"height":61,"caption":"Humanitas"},"image":{"@id":"https:\/\/www.humanitas.net\/sr\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/www.humanitas.net\/sl\/wp-json\/wp\/v2\/treatment\/63147"}],"collection":[{"href":"https:\/\/www.humanitas.net\/sl\/wp-json\/wp\/v2\/treatment"}],"about":[{"href":"https:\/\/www.humanitas.net\/sl\/wp-json\/wp\/v2\/types\/treatment"}],"author":[{"embeddable":true,"href":"https:\/\/www.humanitas.net\/sl\/wp-json\/wp\/v2\/users\/11"}],"version-history":[{"count":0,"href":"https:\/\/www.humanitas.net\/sl\/wp-json\/wp\/v2\/treatment\/63147\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.humanitas.net\/sl\/wp-json\/wp\/v2\/media?parent=63147"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}