{"id":61831,"date":"2020-05-20T12:54:52","date_gmt":"2020-05-20T12:54:52","guid":{"rendered":"https:\/\/www.humanitas.net\/?post_type=disease&p=61831"},"modified":"2020-11-04T15:40:39","modified_gmt":"2020-11-04T15:40:39","slug":"antifosfolipidni-sindrom-aps","status":"publish","type":"disease","link":"https:\/\/www.humanitas.net\/sl\/diseases\/antifosfolipidni-sindrom-aps\/","title":{"rendered":"Antifosfolipidni sindrom (APS)"},"content":{"rendered":"

Antifosfolipidni sindrom (APS) je motnja, ki se klini\u010dno manifestira kot ponavljajo\u010da se venska ali arterijska tromboza in \/ ali izguba ploda. Pojavi se, ko imunski sistem napa\u010dno napade nekatere normalne beljakovine v krvi. Antifosfolipidni sindrom lahko povzro\u010di nastanek krvnih strdkov znotraj arterij ali \u017eil. Prav tako lahko povzro\u010di nose\u010dnostne zaplete, kot so splav in mrtvorojenost.<\/p>\n

Antifosfolipidni sindrom lahko povzro\u010di nastanek krvnih strdkov v venah nog (globoka venska tromboza), pa tudi v organih, kot so ledvice ali plju\u010da, celo strdek v mo\u017eganih, ki lahko povzro\u010di mo\u017egansko kap.<\/p>\n

Simptomi<\/h2>\n

Simptomi antifosfolipidnega sindroma so lahko:<\/p>\n

Ponavljajo\u010da se splava ali mrtvorojenost in drugi zapleti nose\u010dnosti, kot so prezgodnji porod in visok krvni tlak med nose\u010dnostjo (preeklampsija),<\/p>\n

Krvni strdki v nogah (globoka venska tromboza ali DVT), ki lahko potujejo v plju\u010da (plju\u010dna embolija),<\/p>\n

Mo\u017eganska kap,<\/p>\n

Krvni strdki v arterijah rok ali nog (periferna arterijska tromboza).<\/p>\n

Pa tudi nevrolo\u0161ke simptome, izpu\u0161\u010daje, sr\u010dno-\u017eilne bolezni in krvavitve.<\/p>\n

Vzroki<\/h2>\n

Pri sindromu antifosfolipida telo napa\u010dno proizvaja protitelesa proti beljakovinam, ki ve\u017eejo fosfolipide, vrsto ma\u0161\u010dob, prisotnih v krvi, ki igrajo klju\u010dno vlogo pri koagulaciji. Protitelesa so specializirani proteini, ki obi\u010dajno napadajo telesne napadalce, kot so virusi in bakterije. Ko protitelesa napadejo beljakovine, ki ve\u017eejo fosfolipid, se kri lahko nenormalno strdi.<\/p>\n

Nekateri dejavniki, kot so oku\u017ebe, zdravila in genetske nagnjenosti, so povezani z razvijanjem antifosfolipidnih protiteles.<\/p>\n

Faktorji tveganja<\/h2>\n

Dejavniki tveganja za antifosfolipidni sindrom vklju\u010dujejo:<\/p>\n

Imajo avtoimunsko stanje, kot sta sistemski eritematozni lupus ali Sjogrenov sindrom,<\/p>\n

Imajo nekatere oku\u017ebe, kot so sifilis, HIV \/ AIDS, hepatitis C ali lymska bolezen,<\/p>\n

Jemanje dolo\u010denih zdravil, kot so hidralazin za povi\u0161an krvni tlak, kinidin, ki uravnava sr\u010dni ritem, zdravilo proti napadu fenitoin (Dilantin) in antibiotik amoksicilin,<\/p>\n

Imeti dru\u017einskega \u010dlana z antifosfolipidnim sindromom.<\/p>\n

Zapleti<\/h2>\n

Nezdravljeni antifosfolipidni sindrom lahko privede do trajnih okvar ali smrti, odvisno od tega, na kateri organ vpliva krvni strdek in kako mo\u010dna je ovira pretoka krvi v ta organ. Zapleti lahko vklju\u010dujejo:<\/p>\n

Odpoved ledvic,<\/p>\n

Mo\u017eganska kap,<\/p>\n

Sr\u010dno-\u017eilne te\u017eave,<\/p>\n

Te\u017eave s plju\u010di,<\/p>\n

Zapleti v nose\u010dnosti.<\/p>\n

Prepre\u010devanje<\/h2>\n

\u010ce imate antifosfolipidna protitelesa, vendar ne jemljete antikoagulantnih zdravil, upo\u0161tevajte naslednje:<\/p>\n

Obvestite zdravnika, da imate antifosfolipidna protitelesa.<\/p>\n

\u010ce se zaradi kirur\u0161kega posega ali drugih zdravstvenih razlogov ne morete premikati, sprejmete ukrepe za prepre\u010devanje globoke venske tromboze.<\/p>\n

Ne kadite.<\/p>\n

Naredite korake, na primer zni\u017eanje ravni holesterola, da prepre\u010dite sr\u010dni infarkt ali mo\u017egansko kap.<\/p>\n","protected":false},"author":11,"featured_media":0,"template":"","yoast_head":"\nAntifosfolipidni sindrom (APS) - Humanitas.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.humanitas.net\/sl\/diseases\/antifosfolipidni-sindrom-aps\/\" \/>\n<meta property=\"og:locale\" content=\"sl_SI\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Antifosfolipidni sindrom (APS) - Humanitas.net\" \/>\n<meta property=\"og:description\" content=\"Antifosfolipidni sindrom (APS) je motnja, ki se klini\u010dno manifestira kot ponavljajo\u010da se venska ali arterijska tromboza in \/ ali izguba ploda. Pojavi se, ko imunski sistem napa\u010dno napade nekatere normalne beljakovine v krvi. Antifosfolipidni sindrom lahko povzro\u010di nastanek krvnih strdkov znotraj arterij ali \u017eil. Prav tako lahko povzro\u010di nose\u010dnostne zaplete, kot so splav in mrtvorojenost. […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.humanitas.net\/sl\/diseases\/antifosfolipidni-sindrom-aps\/\" \/>\n<meta property=\"og:site_name\" content=\"Humanitas.net\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/HumanitasInternational\/\" \/>\n<meta property=\"article:modified_time\" content=\"2020-11-04T15:40:39+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary\" \/>\n<meta name=\"twitter:site\" content=\"@humanitasmilano\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.humanitas.net\/sl\/diseases\/antifosfolipidni-sindrom-aps\/\",\"url\":\"https:\/\/www.humanitas.net\/sl\/diseases\/antifosfolipidni-sindrom-aps\/\",\"name\":\"Antifosfolipidni sindrom (APS) - Humanitas.net\",\"isPartOf\":{\"@id\":\"https:\/\/www.humanitas.net\/sr\/#website\"},\"datePublished\":\"2020-05-20T12:54:52+00:00\",\"dateModified\":\"2020-11-04T15:40:39+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.humanitas.net\/sl\/diseases\/antifosfolipidni-sindrom-aps\/#breadcrumb\"},\"inLanguage\":\"sl-SI\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.humanitas.net\/sl\/diseases\/antifosfolipidni-sindrom-aps\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.humanitas.net\/sl\/diseases\/antifosfolipidni-sindrom-aps\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.humanitas.net\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Bolesti\",\"item\":\"https:\/\/www.humanitas.net\/sr\/diseases\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Antifosfolipidni sindrom (APS)\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.humanitas.net\/sr\/#website\",\"url\":\"https:\/\/www.humanitas.net\/sr\/\",\"name\":\"Humanitas.net\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/www.humanitas.net\/sr\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.humanitas.net\/sr\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"sl-SI\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.humanitas.net\/sr\/#organization\",\"name\":\"Humanitas\",\"url\":\"https:\/\/www.humanitas.net\/sr\/\",\"sameAs\":[\"https:\/\/www.facebook.com\/HumanitasInternational\/\",\"https:\/\/twitter.com\/humanitasmilano\"],\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"sl-SI\",\"@id\":\"https:\/\/www.humanitas.net\/sr\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.humanitas.net\/content\/uploads\/2017\/05\/logo-news-.png\",\"contentUrl\":\"https:\/\/www.humanitas.net\/content\/uploads\/2017\/05\/logo-news-.png\",\"width\":314,\"height\":61,\"caption\":\"Humanitas\"},\"image\":{\"@id\":\"https:\/\/www.humanitas.net\/sr\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Antifosfolipidni sindrom (APS) - Humanitas.net","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.humanitas.net\/sl\/diseases\/antifosfolipidni-sindrom-aps\/","og_locale":"sl_SI","og_type":"article","og_title":"Antifosfolipidni sindrom (APS) - Humanitas.net","og_description":"Antifosfolipidni sindrom (APS) je motnja, ki se klini\u010dno manifestira kot ponavljajo\u010da se venska ali arterijska tromboza in \/ ali izguba ploda. Pojavi se, ko imunski sistem napa\u010dno napade nekatere normalne beljakovine v krvi. Antifosfolipidni sindrom lahko povzro\u010di nastanek krvnih strdkov znotraj arterij ali \u017eil. Prav tako lahko povzro\u010di nose\u010dnostne zaplete, kot so splav in mrtvorojenost. […]","og_url":"https:\/\/www.humanitas.net\/sl\/diseases\/antifosfolipidni-sindrom-aps\/","og_site_name":"Humanitas.net","article_publisher":"https:\/\/www.facebook.com\/HumanitasInternational\/","article_modified_time":"2020-11-04T15:40:39+00:00","twitter_card":"summary","twitter_site":"@humanitasmilano","twitter_misc":{"Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.humanitas.net\/sl\/diseases\/antifosfolipidni-sindrom-aps\/","url":"https:\/\/www.humanitas.net\/sl\/diseases\/antifosfolipidni-sindrom-aps\/","name":"Antifosfolipidni sindrom (APS) - Humanitas.net","isPartOf":{"@id":"https:\/\/www.humanitas.net\/sr\/#website"},"datePublished":"2020-05-20T12:54:52+00:00","dateModified":"2020-11-04T15:40:39+00:00","breadcrumb":{"@id":"https:\/\/www.humanitas.net\/sl\/diseases\/antifosfolipidni-sindrom-aps\/#breadcrumb"},"inLanguage":"sl-SI","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.humanitas.net\/sl\/diseases\/antifosfolipidni-sindrom-aps\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.humanitas.net\/sl\/diseases\/antifosfolipidni-sindrom-aps\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.humanitas.net\/"},{"@type":"ListItem","position":2,"name":"Bolesti","item":"https:\/\/www.humanitas.net\/sr\/diseases\/"},{"@type":"ListItem","position":3,"name":"Antifosfolipidni sindrom (APS)"}]},{"@type":"WebSite","@id":"https:\/\/www.humanitas.net\/sr\/#website","url":"https:\/\/www.humanitas.net\/sr\/","name":"Humanitas.net","description":"","publisher":{"@id":"https:\/\/www.humanitas.net\/sr\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.humanitas.net\/sr\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"sl-SI"},{"@type":"Organization","@id":"https:\/\/www.humanitas.net\/sr\/#organization","name":"Humanitas","url":"https:\/\/www.humanitas.net\/sr\/","sameAs":["https:\/\/www.facebook.com\/HumanitasInternational\/","https:\/\/twitter.com\/humanitasmilano"],"logo":{"@type":"ImageObject","inLanguage":"sl-SI","@id":"https:\/\/www.humanitas.net\/sr\/#\/schema\/logo\/image\/","url":"https:\/\/www.humanitas.net\/content\/uploads\/2017\/05\/logo-news-.png","contentUrl":"https:\/\/www.humanitas.net\/content\/uploads\/2017\/05\/logo-news-.png","width":314,"height":61,"caption":"Humanitas"},"image":{"@id":"https:\/\/www.humanitas.net\/sr\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/www.humanitas.net\/sl\/wp-json\/wp\/v2\/disease\/61831"}],"collection":[{"href":"https:\/\/www.humanitas.net\/sl\/wp-json\/wp\/v2\/disease"}],"about":[{"href":"https:\/\/www.humanitas.net\/sl\/wp-json\/wp\/v2\/types\/disease"}],"author":[{"embeddable":true,"href":"https:\/\/www.humanitas.net\/sl\/wp-json\/wp\/v2\/users\/11"}],"version-history":[{"count":0,"href":"https:\/\/www.humanitas.net\/sl\/wp-json\/wp\/v2\/disease\/61831\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.humanitas.net\/sl\/wp-json\/wp\/v2\/media?parent=61831"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}