Among the various symptoms and discomforts of premenstrual syndrome, one of the most annoying is precisely the cycle headache. However, – explains Dr. Vincenzo Tullo, neurologist and head of the Humanitas migraine clinic – premenstrual headaches can be relieved by taking a precious mineral salt, magnesium, one week prior to the cycle. The magnesium pidolate, i.e. a magnesium salt that helps magnesium enter the cell where it is most needed, improves mood, stimulates the transmission of nerve impulses and muscle contraction. In order to enjoy its benefits, magnesium must be taken from one week before menstrual cycle begins until the end of menstruation. The intake of magnesium is so effective that it is included in preventive therapies to relieve the symptoms of premenstrual syndrome. In addition to magnesium, the intake of an analgesic of the triptane family from 4-5 days before the start of the cycle is also part of the preventive therapy strategy for premenstrual syndrome symptoms. In the case of premenstrual headaches, symptomatic therapy may also be used: in this case, the symptoms are treated when they occur. Symptomatic therapy involves the intake of paracetamol, non-steroidal anti-inflammatory drugs and triptanes. The latter drugs act on serotonin, commonly called “happiness hormone”. These are also effective solutions and provide rapid relief. However, if the headache persists, is very intense and the solutions listed above do not show any beneficial effects, it is important to consult a specialist and carry out a neurological examination to find a suitable therapy and recover wellbeing.