{"id":57896,"date":"2019-01-31T17:19:11","date_gmt":"2019-01-31T17:19:11","guid":{"rendered":"https:\/\/www.humanitas.net\/?post_type=wiki&#038;p=57896"},"modified":"2019-01-31T17:19:11","modified_gmt":"2019-01-31T17:19:11","slug":"labetalol","status":"publish","type":"wiki","link":"https:\/\/www.humanitas.net\/fr\/wiki\/ingredients-actifs-2\/labetalol\/","title":{"rendered":"Lab\u00e9talol"},"content":{"rendered":"<p>Le lab\u00e9talol est un m\u00e9dicament antihypertenseur qui agit en bloquant simultan\u00e9ment deux types de r\u00e9cepteurs, les r\u00e9cepteurs alpha et b\u00eata-adr\u00e9nergiques. Il agit en inhibant ce premier au niveau des petites art\u00e8res en r\u00e9duisant la r\u00e9sistance au passage sanguin, tandis que l&#8217;inhibition des r\u00e9cepteurs b\u00eata r\u00e9duit les effets secondaires de la vasodilatation dans le c\u0153ur. Ensemble, ces deux actions ont pour effet de r\u00e9duire la tension art\u00e9rielle.<\/p>\n<p>&nbsp;<\/p>\n<h2>Qu&#8217;est-ce que le lab\u00e9talol ?<\/h2>\n<p>&nbsp;<\/p>\n<p>Le lab\u00e9talol est utilis\u00e9 en cas d&#8217;hypertension art\u00e9rielle (\u00e9galement pendant la grossesse) et apr\u00e8s un infarctus du myocarde. Il peut \u00e9galement \u00eatre utilis\u00e9 en cas de crise d&#8217;hypertension et pour traiter l&#8217;hypotension pendant l&#8217;anesth\u00e9sie g\u00e9n\u00e9rale.<\/p>\n<h2><\/h2>\n<h2>Comment faut-il prendre le lab\u00e9talol ?<\/h2>\n<p>Le lab\u00e9talol se pr\u00e9sente sous forme de comprim\u00e9s \u00e0 100 mg avec une dose initiale de 2 fois par jour (matin et soir), toujours l&#8217;estomac plein. Par la suite, et si n\u00e9cessaire, la dose peut \u00eatre augment\u00e9e jusqu&#8217;\u00e0 200 mg 2 fois par jour. Toutefois, il n&#8217;est pas \u00e0 exclure que, dans des cas particuli\u00e8rement r\u00e9sistants, l&#8217;\u00e9tat puisse exiger de prendre m\u00eame deux doses de 400 mg par jour. La dose maximale qui peut \u00eatre administr\u00e9e est de 2,4 grammes par jour au total.<\/p>\n<p>&nbsp;<\/p>\n<h2>Effets secondaires associ\u00e9s au lab\u00e9talol<\/h2>\n<p>Les effets secondaires possibles du lab\u00e9talol peuvent inclure :<\/p>\n<ul>\n<li>Changements dans la composition du sang<\/li>\n<li>\u0152d\u00e8me de Quincke<\/li>\n<li>Asth\u00e9nie<\/li>\n<li>\u00c9l\u00e9vations dans les tests de la fonction h\u00e9patique<\/li>\n<li>Bradycardie<\/li>\n<li>Bronchospasme<\/li>\n<li>Congestion nasale<\/li>\n<li>Dommages au foie<\/li>\n<li>D\u00e9pression<\/li>\n<li>Dyspn\u00e9e<\/li>\n<li>Troubles de la conduction cardiaque<\/li>\n<li>Troubles de la miction<\/li>\n<li>Mauvaise vue<\/li>\n<li>Douleurs \u00e9pigastriques<\/li>\n<li>\u0152d\u00e8me de la cheville<\/li>\n<li>H\u00e9patite<\/li>\n<li>\u00c9ruptions cutan\u00e9es<\/li>\n<li>\u00c9ruptions lich\u00e9no\u00efdes<\/li>\n<li>Temp\u00e9rature<\/li>\n<li>Picotements du cuir chevelu<\/li>\n<li>Hypotension posturale<\/li>\n<li>Jaunisse<\/li>\n<li>L\u00e9thargie<\/li>\n<li>Lupus \u00e9ryth\u00e9mateux diss\u00e9min\u00e9<\/li>\n<li>Maux de t\u00eate<\/li>\n<li>\u00c9chec de l&#8217;\u00e9jaculation<\/li>\n<li>Myopathie toxique<\/li>\n<li>Naus\u00e9es<\/li>\n<li>N\u00e9crose h\u00e9patique<\/li>\n<li>Anticorps antinucl\u00e9aires positifs<\/li>\n<li>D\u00e9mangeaisons<\/li>\n<li>R\u00e9tention urinaire aigu\u00eb<\/li>\n<li>S\u00e9cheresse de la muqueuse nasale<\/li>\n<li>S\u00e9cheresse et irritation des yeux<\/li>\n<li>R\u00eaves vifs<\/li>\n<li>Transpiration<\/li>\n<li>Tremblements<\/li>\n<li>\u00c9tourdissements<\/li>\n<li>Vomissements<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h2>Contre-indications et mises en garde associ\u00e9es \u00e0 l&#8217;utilisation de lab\u00e9talol<\/h2>\n<p>Le lab\u00e9talol ne doit pas \u00eatre pris en cas de :<\/p>\n<ul>\n<li>Acidose diab\u00e9tique<\/li>\n<li>Allaitement (allaitement maternel)<\/li>\n<li>Bloc auriculo-ventriculaire du deuxi\u00e8me ou troisi\u00e8me degr\u00e9<\/li>\n<li>Bradycardie grave marqu\u00e9e<\/li>\n<li>Insuffisance cardiaque r\u00e9sistante au traitement par digitaline<\/li>\n<li>Insuffisance r\u00e9nale grave<\/li>\n<li>Hypersensibilit\u00e9 \u00e0 la substance active ou \u00e0 l&#8217;un des ingr\u00e9dients du m\u00e9dicament (notamment le lactose)<\/li>\n<li>Choc cardiog\u00e9nique et autres conditions associ\u00e9es \u00e0 une hypotension grave et prolong\u00e9e<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>Il est \u00e9galement important d&#8217;\u00eatre attentif ou de prendre des pr\u00e9cautions particuli\u00e8res en cas de :<\/p>\n<ul>\n<li>Asthme et bronchospasme<\/li>\n<li>Dommages au foie<\/li>\n<li>Insuffisance cardiaque<\/li>\n<li><\/li>\n<\/ul>\n<p>Les m\u00e9dicaments avec lesquels il peut interagir incluent notamment\u00a0:<\/p>\n<ul>\n<li>Bloqueurs des canaux calciques du type v\u00e9rapamil<\/li>\n<li>Un antiarythmique de classe I<\/li>\n<li>Amiodarone<\/li>\n<li>Anesth\u00e9siques<\/li>\n<li>Antid\u00e9presseurs tricycliques<\/li>\n<li>Cim\u00e9tidine<\/li>\n<\/ul>\n<p>Enfin, puisqu&#8217;il peut causer des \u00e9tourdissements et de la l\u00e9thargie, le lab\u00e9talol doit \u00eatre pris avec prudence lorsque vous devez conduire ou man\u0153uvrer une machine dangereuse.<\/p>\n","protected":false},"author":11,"featured_media":0,"template":"","wiki-categories":[2224],"wiki-types":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.7.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Lab\u00e9talol - Humanitas.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.humanitas.net\/fr\/wiki\/ingredients-actifs-2\/labetalol\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Lab\u00e9talol - Humanitas.net\" \/>\n<meta property=\"og:description\" content=\"Le lab\u00e9talol est un m\u00e9dicament antihypertenseur qui agit en bloquant simultan\u00e9ment deux types de r\u00e9cepteurs, les r\u00e9cepteurs alpha et b\u00eata-adr\u00e9nergiques. 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