{"id":57226,"date":"2019-01-30T17:58:16","date_gmt":"2019-01-30T17:58:16","guid":{"rendered":"https:\/\/www.humanitas.net\/?post_type=wiki&#038;p=57226"},"modified":"2019-01-30T17:58:16","modified_gmt":"2019-01-30T17:58:16","slug":"entacapone","status":"publish","type":"wiki","link":"https:\/\/www.humanitas.net\/fr\/wiki\/ingredients-actifs-2\/entacapone\/","title":{"rendered":"Entacapone"},"content":{"rendered":"<p>L&#8217;entacapone est utilis\u00e9e en association avec la l\u00e9vodopa et la carbidopa pour traiter les sympt\u00f4mes de la maladie de Parkinson lorsque les sympt\u00f4mes r\u00e9apparaissent malgr\u00e9 un traitement m\u00e9dicamenteux continu.<\/p>\n<p>&nbsp;<\/p>\n<h2>Qu&#8217;est-ce que l&#8217;entacapone ?<\/h2>\n<p>L&#8217;entacapone est un inhibiteur de l&#8217;enzyme cat\u00e9chol-O-m\u00e9thyltransf\u00e9rase. Il est suppos\u00e9 agir en modifiant la pharmacocin\u00e9tique de la l\u00e9vodopa, un m\u00e9dicament administr\u00e9 dans le traitement de la maladie de Parkinson. Combin\u00e9 avec la l\u00e9vodopa et la carbidopa (ou des mol\u00e9cules similaires), il augmente les niveaux de l\u00e9vodopa dans le sang.<\/p>\n<p>&nbsp;<\/p>\n<h2>Comment faut-il prendre l&#8217;entacapone ?<\/h2>\n<p>G\u00e9n\u00e9ralement, l&#8217;entacapone est administr\u00e9e par voie orale sous forme de comprim\u00e9s et doit \u00eatre prise avec chaque dose de l\u00e9vodopa, jusqu&#8217;\u00e0 huit fois par jour.<\/p>\n<p>&nbsp;<\/p>\n<h2>Effets secondaires associ\u00e9s \u00e0 l&#8217;entacapone<\/h2>\n<p>Les effets secondaires possibles de l&#8217;entacapone sont notamment les suivants :<\/p>\n<ul>\n<li>\u00c9tourdissements<\/li>\n<li>Diarrh\u00e9e<\/li>\n<li>Probl\u00e8mes d&#8217;estomac<\/li>\n<li>Mouvements incontr\u00f4lables<\/li>\n<li>Somnolence<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>Vous devez imm\u00e9diatement consulter votre m\u00e9decin si ce m\u00e9dicament provoque l\u2019un ou l\u2019autre des sympt\u00f4mes suivants :<\/p>\n<ul>\n<li>Difficult\u00e9 \u00e0 respirer<\/li>\n<li>Hallucinations<\/li>\n<li>Fi\u00e8vre \u00e9lev\u00e9e<\/li>\n<li>Confusion<\/li>\n<li>Raideur musculaire<\/li>\n<li>Faiblesse, m\u00eame en cas de fi\u00e8vre<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2>Contre-indications et mises en garde associ\u00e9es \u00e0 l&#8217;utilisation de l&#8217;entacapone<\/h2>\n<p>L&#8217;entacapone peut interf\u00e9rer avec la capacit\u00e9 de conduire et de man\u0153uvrer des machines dangereuses.<\/p>\n<p>Avant de prendre ce m\u00e9dicament, il est important d&#8217;informer votre m\u00e9decin dans les cas suivants :<\/p>\n<ul>\n<li>Si vous avez des allergies \u00e0 la substance active, \u00e0 ses excipients ou \u00e0 d&#8217;autres m\u00e9dicaments ;<\/li>\n<li>Si vous prenez des m\u00e9dicaments, des rem\u00e8des \u00e0 base de plantes ou des suppl\u00e9ments. Et notamment : ampicilline, apomorphine, bitolt\u00e9rol, chloramph\u00e9nicol, cholestyramine, m\u00e9dicaments qui causent la somnolence, dobutamine, \u00e9pin\u00e9phrine (adr\u00e9naline), \u00e9rythromycine, iso\u00e9tarine, isoprot\u00e9r\u00e9nol, m\u00e9thyldopa, ph\u00e9nelzine, prob\u00e9n\u00e9cid, rifampine, tranylcypromine et vitamines ;<\/li>\n<li>Si vous souffrez (ou avez souffert) d&#8217;une maladie du foie ou d&#8217;alcoolisme ;<\/li>\n<li>Si vous \u00eates enceinte ou si vous allaitez<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>Il est important d&#8217;informer les chirurgiens ou les dentistes de tout traitement en cours \u00e0 base d&#8217;entacapone.<\/p>\n","protected":false},"author":11,"featured_media":0,"template":"","wiki-categories":[2224],"wiki-types":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.7.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Entacapone - Humanitas.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.humanitas.net\/fr\/wiki\/ingredients-actifs-2\/entacapone\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Entacapone - Humanitas.net\" \/>\n<meta property=\"og:description\" content=\"L&#8217;entacapone est utilis\u00e9e en association avec la l\u00e9vodopa et la carbidopa pour traiter les sympt\u00f4mes de la maladie de Parkinson lorsque les sympt\u00f4mes r\u00e9apparaissent malgr\u00e9 un traitement m\u00e9dicamenteux continu. &nbsp; Qu&#8217;est-ce que l&#8217;entacapone ? 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