{"id":57185,"date":"2019-01-30T17:35:47","date_gmt":"2019-01-30T17:35:47","guid":{"rendered":"https:\/\/www.humanitas.net\/?post_type=wiki&#038;p=57185"},"modified":"2019-01-30T17:35:47","modified_gmt":"2019-01-30T17:35:47","slug":"ceftazidime","status":"publish","type":"wiki","link":"https:\/\/www.humanitas.net\/fr\/wiki\/ingredients-actifs-2\/ceftazidime\/","title":{"rendered":"Ceftazidime"},"content":{"rendered":"<p>La ceftazidime est un antibiotique qui appartient au groupe des c\u00e9phalosporines de troisi\u00e8me g\u00e9n\u00e9ration. Elle a une activit\u00e9 antimicrobienne similaire \u00e0 celle du c\u00e9fotaxime et lutte contre les bact\u00e9ries \u00e0 Gram positif et les ent\u00e9robact\u00e9ries. Elle agit en inhibant la synth\u00e8se de la paroi bact\u00e9rienne. Comme les autres c\u00e9phalosporines, cet antibiotique a la capacit\u00e9 de se lier aux enzymes transpeptidases qui servent \u00e0 cr\u00e9er les liaisons entre les cha\u00eenes peptidoglycanes (les polym\u00e8res essentiels \u00e0 la constitution de la paroi bact\u00e9rienne). En retour, l&#8217;activit\u00e9 transpeptidase emp\u00eache la stabilit\u00e9 de la paroi cellulaire bact\u00e9rienne, ce qui entra\u00eene la mort des cellules bact\u00e9riennes en croissance.<\/p>\n<p>&nbsp;<\/p>\n<h2>Qu&#8217;est-ce que la ceftazidime ?<\/h2>\n<p>La ceftazidime est utilis\u00e9e dans le traitement des infections suivantes qui sont sensibles aux c\u00e9phalosporines chez les adultes, les enfants et les nourrissons :<\/p>\n<ul>\n<li>Infections des voies respiratoires comme la pneumonie ;<\/li>\n<li>Infections pulmonaires chez les patients atteints de fibrose kystique ;<\/li>\n<li>Infections des voies urinaires ;<\/li>\n<li>Infections de la peau, des tissus mous, des os et des articulations ;<\/li>\n<li>Infections de l&#8217;oreille ;<\/li>\n<li>P\u00e9ritonite ;<\/li>\n<li>Septic\u00e9mie ;<\/li>\n<li>M\u00e9ningite<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2>Comment faut-il prendre la ceftazidime ?<\/h2>\n<p>La ceftazidime est prise sous forme de poudre et de solvant par injection. Elle peut \u00eatre administr\u00e9e par voie intramusculaire, intraveineuse ou en solution pour perfusion.<\/p>\n<p>&nbsp;<\/p>\n<h2>Effets secondaires associ\u00e9s \u00e0 la ceftazidime<\/h2>\n<p>Il existe plusieurs effets secondaires connus de l&#8217;utilisation de la ceftazidime, bien qu\u2019elle semble \u00eatre un antibiotique g\u00e9n\u00e9ralement bien tol\u00e9r\u00e9. Les effets secondaires possibles sont notamment les suivants :<\/p>\n<ul>\n<li>Troubles au point d&#8217;injection (phl\u00e9bite ou thrombophl\u00e9bite avec administration intraveineuse ; douleur et\/ou inflammation r\u00e9sultant de l&#8217;administration intramusculaire) ;<\/li>\n<li>R\u00e9actions allergiques : \u00e9ruption maculopapuleuse ou urticaire, d\u00e9mangeaisons, fi\u00e8vre, \u0153d\u00e8me angioneurotique rare et r\u00e9actions anaphylactiques (y compris bronchospasme et \/ ou hypotension).<\/li>\n<li>Troubles gastro-intestinaux : diarrh\u00e9e, naus\u00e9es, vomissements, douleurs abdominales, colite plus rare et candidose de la cavit\u00e9 orale ;<\/li>\n<li>Troubles g\u00e9nito-urinaires : candidose, vaginite ;<\/li>\n<li>Troubles neurologiques : maux de t\u00eate, \u00e9tourdissements, paresth\u00e9sies ;<\/li>\n<li>Anomalies des fonctions r\u00e9nales et h\u00e9patiques<\/li>\n<li>Troubles h\u00e9matologiques (rares) : leucop\u00e9nie, neutrop\u00e9nie, agranulocytose, thrombocytop\u00e9nie et lymphocytose.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2>Contre-indications et mises en garde associ\u00e9es \u00e0 l&#8217;utilisation de la ceftazidime<\/h2>\n<p>La quantit\u00e9 limit\u00e9e de donn\u00e9es recueillies sur l&#8217;utilisation de la ceftazidime pendant la grossesse ne met en \u00e9vidence aucun effet nocif direct ou indirect sur la grossesse elle-m\u00eame, comme le d\u00e9veloppement embryonnaire\/f\u0153tal, la parturition ou le d\u00e9veloppement post-natal. Pour cette raison, l&#8217;utilisation de cet antibiotique ne doit \u00eatre prescrite aux femmes enceintes que si les bienfaits l&#8217;emportent sur les risques. La ceftazidime s&#8217;accumule dans le lait maternel en petites quantit\u00e9s et il n&#8217;y a donc aucune contre-indication \u00e0 son utilisation pendant l&#8217;allaitement.<\/p>\n<p>Aucune \u00e9tude n&#8217;a \u00e9t\u00e9 r\u00e9alis\u00e9e sur la capacit\u00e9 de conduire et de man\u0153uvrer des machines pendant la prise de ceftazidime. Toutefois, il est conseill\u00e9 de garder \u00e0 l&#8217;esprit que l&#8217;utilisation de ce m\u00e9dicament peut causer des \u00e9tourdissements. Pendant l&#8217;injection de ce m\u00e9dicament, il est conseill\u00e9 de consid\u00e9rer que le traitement concomitant avec des doses \u00e9lev\u00e9es de c\u00e9phalosporines et de m\u00e9dicaments n\u00e9phrotoxiques peut avoir un effet n\u00e9gatif sur la fonction r\u00e9nale<\/p>\n","protected":false},"author":11,"featured_media":0,"template":"","wiki-categories":[2224],"wiki-types":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.7.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Ceftazidime - Humanitas.net<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.humanitas.net\/fr\/wiki\/ingredients-actifs-2\/ceftazidime\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ceftazidime - Humanitas.net\" \/>\n<meta property=\"og:description\" content=\"La ceftazidime est un antibiotique qui appartient au groupe des c\u00e9phalosporines de troisi\u00e8me g\u00e9n\u00e9ration. 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