Piroxcam is used in treatments for osteoarthritis and rheumatoid arthritis.

What is Piroxcam?

Piroxcam is an anti-inflammatory drug (NSAIDs). Even though the exact mechanism of action is not known, it appears to work by blocking the effects of substances responsible for inflammation.

How should Piroxcam be taken?

Piroxcam is administered orally, for example in the form of capsules.

Side effects associated with Piroxcam

Piroxcam can be associated with ulcers or gastrointestinal bleeding. It may also reduce the number of platelets, raising the pressure, trigger severe skin reactions or liver problems.

Among the other possible adverse effects are included:

  • Constipation
  • Diarrhea
  • Dizziness
  • Gas
  • Headache
  • Heartburn
  • Nausea
  • Upset stomach or other stomach discomfort
  • Vomiting

You should immediately contact a doctor if taking Piroxcam triggers any of the following symptoms:

  • Rash
  • Urticaria
  • Itchy skin
  • Difficult breathing
  • Feeling of tightness or pain in the chest
  • Swelling of the mouth, face, lips, or tongue
  • Confusion
  • Depression
  • Fainting
  • Rapid or irregular heartbeat
  • Fever, chills or persistent sore throat
  • Changes in mood or behavior
  • Numbness of arms or legs
  • Weakness in one side of the body
  • Tinnitus
  • Convulsions
  • Headache and severe or persistent dizziness
  • Stomach pain, nausea or vomiting (severe or persistent)
  • Shortness of breath
  • Sudden or unreasonable weight gain
  • Swelling of the hands, legs or feet
  • Bleeding
  • Kidney problems
  • Unusual muscle or joint pain
  • Unusual tiredness or weakness
  • Vision or talking problems

Contraindications and warnings associated with the use of Piroxcam

Moreover, before starting the treatment it is important to tell your doctor if:

  • You have any allergies to the active substance, its supstances, other medications (especially aspirin or other NSAIDs) or any food
  • You are taking other medications, herbal remedies and supplements, especially anticoagulants, aspirin, clopidogrel, corticosteroids, heparin, rivaroxaban, SSRI, probenecid, cholestyramine, bisphosphonates, cyclosporine, hydantoins, lithium, methotrexate, quinolones, sulfonamides, sulfonylureas, ACE inhibitors or diuretics
  • You suffer (or have suffered) from gastrointestinal bleeding, kidney or liver disease, diabetes, gastrointestinal problems, fluid retention or swelling, asthma, nasal polyps, oral inflammation, high blood pressure, blood disorders, bleeding or blood clots, cardiovascular problems, dehydration, hypovolemia and low levels of sodium in the blood
  • You have fertility problems or undergoing examinations and treatments for fertility problems
  • You smoke, drink alcohol or have a history of alcoholism
  • You have a planned or had a recent heart bypass surgery
  • You are pregnant or breastfeeding

It is recommended to inform physicians, surgeons and dentists about ongoing treatment with Piroxcam prior to any procedure.