Mitotane is used to treat adrenal cortical cancer that cannot be treated with surgery.
What is Mitotane?
Mitotane is an adrenal cytotoxic agent . Its exact mechanism of action has not yet been identified. It may work by slowing down the function of the adrenal gland.
How should Mitotane be taken?
Mitotane is administered orally in the form of tablets.
Side effects associated with Mitotane
Among the possible side effects of mitotane include the following:
- Diarrhea
- Dizziness
- Drowsiness
- Lack of energy
- Loss of appetite
- Nausea
- Fatigue
- Vomiting
It is important to contact a doctor immediately if you experience:
- Rash
- Urticaria
- Difficulty breathing
- Tightness in the chest
- Swelling of the mouth, face, lips or tongue
- Bloody urine
- Vision problems
- Confusion
- Depression
- Fainting
- Persistent fever, chills or sore throat
- Severe or persistent dizziness
- Drowsiness
- Headache
- Feeling faint or lightheaded
- Fatigue
Contraindications and warnings associated with the use of Mitotane
Mitotane is contraindicated in case of severe trauma or shock. The intake of the drug can impair the ability to drive or operate hazardous machinery. This side effect may be aggravated by alcohol and certain other medications.
Before starting treatment with mitotane, it is important to tell your doctor if:
- You have any allergies to the active substance, its excipients or to any other drugs, food or various substances
- You are taking any other medications (in particular anticoagulants), herbal remedies or supplements
- You are suffering (or have suffered) from other liver problems
- You are planning on undergoing surgery
- You are pregnant or breast-feeding
It is important to inform physicians, surgeons and dentists of any ongoing treatment with mitotane.
Women of childbearing age must use effective birth control methods during treatment and for an appropriate amount of time after discontinuation.
