Metirosine is used to reduce the increase of catecholamines associated with some types of cancer, in particular pheochromocytoma that can develop in the adrenal gland.
It is used both as a preliminary treatment to surgery and as a long-term treatment of the symptoms associated with this form of cancer.
What is Metirosine?
Metirosine works by inhibiting the synthesis of the substances called catecholamines, whose production increases significantly in the presence of some cancers. The result is a reduction in the quantities of these molecules in the body.
How should Metirosine be taken?
Metirosine is administered orally.
Side effects associated with Metirosine
The possible adverse effects of Metirosina may include drowsiness.
It is important to contact a doctor immediately if taking Metirosine triggers any of the following symptoms:
- Rash
- Urticaria
- Difficulty breathing
- Tightness in the chest
- Swelling of the mouth, face, lips, or tongue
- Anxiety
- Confusion
- Presence of crystals in the urine
- Depression
- Diarrhea
- Difficulty speaking
- Disorientation
- Drooling from the mouth
- Hallucinations
- Painful urination
- Swelling of arms, legs, ankles or feet
- Tremors
Contraindications and warnings associated with the use of Metirosine
Before taking Metirosine it is important to tell your doctor if:
- You have any allergies to the active substance, to other components, any other drug, food or other substances
- You are taking other medications, herbal remedies and supplements, particularly medicines that make you sleepy (medicines for insomnia or against anxiety and tranquilizers), haloperidol and phenothiazines
- You suffer (or have suffered) from any diseases or health conditions
- You drink alcohol
- You are pregnant or breastfeeding
Furthermore, it is important to inform physicians, surgeons or dentists about ongoing treatment with Metirosine prior to any procedure.
Lastly, the treatment may impair the ability to drive or operate hazardous machinery. This side effect can be aggravated by alcohol or other drugs.
