Methylergonovine is used to treat bleeding during and after childbirth.
What is Methylergonovine?
Methylergonovine is a uterine stimulant that works by increasing contractions in order to contain blood loss after childbirth.
How should Methylergonovine be taken?
Methylergonovine can be administered intramuscularly or intravenously (via injections) or orally (in the form of tablets). The dosage varies from case to case.
Side effects associated with Methylergonovine
Among the possible side effects of Methylergonovine include the following:
- Headache
- Nausea
- Vomiting
- Abdominal cramps
It is important to contact a doctor immediately if you experience:
- Rash
- Urticaria
- Itch
- Difficulty breathing
- Tightness in chest
- Swelling of the mouth, face, lips or tongue
- Bloody urine
- Burning sensation, tingling, numbness in the fingers
- Pale fingers
- Pain to the chest, jaw or arms
- Confusion
- Dizziness
- Fainting
- Slow, fast or irregular heartbeat
- Hallucinations
- Leg cramps
- Changes in mood or behavior
- Weakness in one side of body
- Tinnitus
- Convulsions
- Severe or persistent headache, nausea, vomiting or stomach pain
- Shortness of breath
- Difficulty speaking
- Sudden or unusual sweating or weakness
- Vision problems
Contraindications and warnings associated with the use of Methylergonovine
Methylergonovine should not be taken in case of high blood pressure or any ongoing treatment with azole antifungals, cobicistat, certain antibiotics, certain protease inhibitors, certain reverse transcriptase inhibitors or triptans. It is also crucial to avoid consuming grapefruit or its juice during treatment.
Before starting treatment with Methylergonovine, it is important to tell your doctor if:
- You have any allergies to the active substance, its excipients, or any other drugs or food
- You are taking any other medications, herbal remedies or supplements. Mentioning in particular: anti-anginal drugs, ergot derivatives, azole antifungals, beta-blockers, clotrimazole, cobicistat, fluoxetine, fluvoxamine, antibiotics, nefazodone, protease inhibitors, reverse transcriptase inhibitors, triptans zileuton, nevirapine or rifamycins
- You are suffering (or have suffered) from blood infections, blood vessel disease, stroke, liver disease, kidney or heart problems, high blood pressure, eclampsia, diabetes or high cholesterol
- You are a smoker
- You are overweight (obese)
- You are breast-feeding
It is important to inform physicians, surgeons and dentists of any ongoing treatment with Methylergonovine.
