Ciprofloxacin owns a high antibacterial activity, in particular against Gram-negative bacteria. It is used to treat many infections of the urinary, respiratory and gastrointestinal tract, as well as gonorrhea and septicemia.
What is Ciprofloxacin?
Ciprofloxacin is a synthetic antibiotic of the family Quinolones (agents capable of inhibiting the synthesis of bacterial DNA during replication and have bactericidal activity towards many Gram-negative bacteria). Ciprofloxacin belongs to the family of second generation Fluoroquinolones and it is therefore equipped with a broader spectrum of actions and excellent pharmacokinetic properties. Despite these features, in the past few years, different microorganisms have shown series of mechanisms of resistance. The mentioned mechanisms can significantly reduce the therapeutic efficacy of this antibiotic, compromising the effectiveness and contributing to the spread of the multi-resistant microbe species.
How should Ciprofloxacin be taken?
Ciprofloxacin is usually administered orally in the form of tablets. The absorption of the drug occurs in the intestine.
Side effects associated with Ciprofloxacin
Generally, the use of this antibiotic is well tolerated.
However, there are some possible adverse effects that may occur, such as:
- Gastrointestinal disturbances (nausea and diarrhea);
- Changes of renal and liver function;
- Photosensitivity;
- Headache, irritability, sleep disturbances;
- Blood alterations;
- Musculoskeletal system diseases and conditions.
Contraindications and warnings associated with the use of Ciprofloxacin
Ciprofloxacin has the ability to be accumulated in the breast milk; therefore it is not recommended for women during their pregnancy. Finally, the use of this antibiotic is also contraindicated during lactation.
